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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 4 hits in this display   

TargetAdenosine receptor A2a(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM26256(N-[2-(3,5-dimethyl-1H-pyrazol-1-yl)-6-[6-(4-methox...)
Affinity DataKi:  0.400nMAssay Description:Inhibition of human recombinant adenosine receptor A2aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM26256(N-[2-(3,5-dimethyl-1H-pyrazol-1-yl)-6-[6-(4-methox...)
Affinity DataKi:  0.440nM ΔG°:  -52.9kJ/molepH: 7.4 T: 2°CAssay Description:The membranes prepared from HEK cells transfected with adenosine receptors were used in binding assays. Nonspecific binding was determined in the pre...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM26256(N-[2-(3,5-dimethyl-1H-pyrazol-1-yl)-6-[6-(4-methox...)
Affinity DataKi:  77nMAssay Description:Inhibition of human recombinant adenosine A1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM26256(N-[2-(3,5-dimethyl-1H-pyrazol-1-yl)-6-[6-(4-methox...)
Affinity DataKi:  85nMAssay Description:The membranes prepared from HEK cells transfected with adenosine receptors were used in binding assays. Nonspecific binding was determined in the pre...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed