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Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
11
hits in this display
Target
Type 1 fimbrin D-mannose specific adhesin
(Escherichia coli (strain K12))
University Of Basel
Curated by
ChEMBL
Ligand
BDBM50166886
(CHEMBL195368 | methyl alpha-D-mannoside)
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Affinity Data
IC50: 1.90E+3nM
Assay Description:
Antagonist activity at Escherichia coli recombinant C-terminal 6His-tagged FimH-CRD with a C-terminal thrombin cleavage site expressed in Escherichia...
More data for this Ligand-Target Pair
Target Info
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Target
Fucose-binding lectin PA-IIL
(Pseudomonas aeruginosa)
Helmholtz Institute For Pharmaceutical Research Saarland (Hips)
Curated by
ChEMBL
Ligand
BDBM50166886
(CHEMBL195368 | methyl alpha-D-mannoside)
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Affinity Data
IC50: 3.70E+4nM
Assay Description:
Competitive inhibition of N-(fluorescein-5-yl)-N'-(alpha-L-fucopyranosyl ethylen)-thiocarbamide binding to Pseudomonas aeruginosa PA14 LecB after 8 t...
More data for this Ligand-Target Pair
Target Info
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MMDB
KEGG
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DrugBank
GoogleScholar
Ligand Info
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ChEBI
CHEMBL
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In Depth
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Target
Fucose-binding lectin PA-IIL
(Pseudomonas aeruginosa)
Helmholtz Institute For Pharmaceutical Research Saarland (Hips)
Curated by
ChEMBL
Ligand
BDBM50166886
(CHEMBL195368 | methyl alpha-D-mannoside)
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Affinity Data
IC50: 4.68E+4nM
Assay Description:
Competitive binding affinity to recombinant Pseudomonas aeruginosa PA14 LecB expressed in Escherichia coli BL21(DE3) incubated for 4 to 8 hrs by fluo...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
KEGG
UniProtKB/TrEMBL
B.MOAD
DrugBank
GoogleScholar
Ligand Info
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ChEBI
CHEMBL
DrugBank
KEGG
MMDB
PC cid
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In Depth
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PubMed
Copy BDB DOI
Target
Fucose-binding lectin PA-IIL
(Pseudomonas aeruginosa)
Helmholtz Institute For Pharmaceutical Research Saarland (Hips)
Curated by
ChEMBL
Ligand
BDBM50166886
(CHEMBL195368 | methyl alpha-D-mannoside)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.04E+5nM
Assay Description:
Competitive binding affinity to recombinant Pseudomonas aeruginosa PAO1 LecB expressed in Escherichia coli BL21(DE3) incubated for 4 to 8 hrs by fluo...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
KEGG
UniProtKB/TrEMBL
B.MOAD
DrugBank
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
KEGG
MMDB
PC cid
PC sid
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In Depth
Details
PubMed
Copy BDB DOI
Target
Fucose-binding lectin PA-IIL
(Pseudomonas aeruginosa)
Helmholtz Institute For Pharmaceutical Research Saarland (Hips)
Curated by
ChEMBL
Ligand
BDBM50166886
(CHEMBL195368 | methyl alpha-D-mannoside)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.57E+5nM
Assay Description:
Inhibition of Pseudomonas aeruginosa PAO1 LecB after 6 hrs by fluorescence polarization assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
KEGG
UniProtKB/TrEMBL
B.MOAD
DrugBank
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
KEGG
MMDB
PC cid
PC sid
Patents
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In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Fucose-binding lectin PA-IIL
(Pseudomonas aeruginosa)
Helmholtz Institute For Pharmaceutical Research Saarland (Hips)
Curated by
ChEMBL
Ligand
BDBM50166886
(CHEMBL195368 | methyl alpha-D-mannoside)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.57E+5nM
Assay Description:
Inhibition of Pseudomonas aeruginosa LecB by fluorescence polarization assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
KEGG
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GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
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KEGG
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PC sid
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In Depth
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Article
PubMed
Copy BDB DOI
Target
Fucose-binding lectin PA-IIL
(Pseudomonas aeruginosa)
Helmholtz Institute For Pharmaceutical Research Saarland (Hips)
Curated by
ChEMBL
Ligand
BDBM103981
(LecB Inhibitor Compound 1)
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Affinity Data
IC50: 1.58E+5nM Kd: 7.10E+4nM
More data for this Ligand-Target Pair
Target Info
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Target
Concanavalin-A
(Canavalia ensiformis)
Georgia Southern University
Curated by
ChEMBL
Ligand
BDBM50166886
(CHEMBL195368 | methyl alpha-D-mannoside)
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Affinity Data
IC50: 3.50E+5nM
Assay Description:
Inhibition of Canavalia ensiformis concanavalin A binding to yeast mannan by ELLA
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Target Info
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Target
C-type lectin domain family 4 member M
(Homo sapiens)
Universit£
Curated by
ChEMBL
Ligand
BDBM50166886
(CHEMBL195368 | methyl alpha-D-mannoside)
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Affinity Data
IC50: 1.27E+6nM
Assay Description:
Inhibition of DC-SIGN (unknown origin) expressed in human Jurkat cells assessed as inhibition of EBOV-pseudotyped virus infection measured after 48 h...
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Target Info
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ChEBI
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PubMed
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Target
PA-I galactophilic lectin
(Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 /...)
Indian Institute Of Technology Bombay
Curated by
ChEMBL
Ligand
BDBM50166886
(CHEMBL195368 | methyl alpha-D-mannoside)
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Affinity Data
Kd: 71nM
Assay Description:
Binding affinity to recombinant Pseudomonas aeruginosa LecA expressed in Escherichia coli BL21 (DE3) expression system assessed as dissociation const...
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
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GoogleScholar
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ChEBI
CHEMBL
DrugBank
KEGG
MMDB
PC cid
PC sid
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In Depth
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PubMed
Copy BDB DOI
Target
Type 1 fimbrin D-mannose specific adhesin
(Escherichia coli (strain K12))
University Of Basel
Curated by
ChEMBL
Ligand
BDBM50166886
(CHEMBL195368 | methyl alpha-D-mannoside)
Copy SMILES
Copy InChI
Affinity Data
Kd: 2.20E+3nM
Assay Description:
Binding affinity to Escherichia coli FimH assessed as dissociation constant by SPR analysis
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
KEGG
MMDB
PC cid
PC sid
Patents
Similars
In Depth
Details
PubMed
Copy BDB DOI