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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
5
hits in this display
Target
Neprilysin
(Rattus norvegicus (Rat))
Pfizer
Curated by
ChEMBL
Ligand
BDBM50197517
((S)-2-{1-[3-(4-chloro-phenyl)-propylcarbamoyl]-cyc...)
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Affinity Data
IC50: 0.600nM
Assay Description:
Inhibition of rat NEP
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Neprilysin
(Oryctolagus cuniculus (rabbit))
Pfizer
Curated by
ChEMBL
Ligand
BDBM50197517
((S)-2-{1-[3-(4-chloro-phenyl)-propylcarbamoyl]-cyc...)
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Affinity Data
IC50: 0.800nM
Assay Description:
Inhibition of rabbit NEP
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Neprilysin
(Homo sapiens (Human))
Pfizer
Curated by
ChEMBL
Ligand
BDBM50197517
((S)-2-{1-[3-(4-chloro-phenyl)-propylcarbamoyl]-cyc...)
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Affinity Data
IC50: 2.30nM
pH: 7.0
Assay Description:
Inhibition of human kidney NEP at pH 7
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Neprilysin
(Homo sapiens (Human))
Pfizer
Curated by
ChEMBL
Ligand
BDBM50197517
((S)-2-{1-[3-(4-chloro-phenyl)-propylcarbamoyl]-cyc...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 5.40nM
Assay Description:
Inhibition of human recombinant NEP
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Neprilysin
(Homo sapiens (Human))
Pfizer
Curated by
ChEMBL
Ligand
BDBM50197517
((S)-2-{1-[3-(4-chloro-phenyl)-propylcarbamoyl]-cyc...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 10.5nM
pH: 7.4
Assay Description:
Inhibition of human kidney NEP at pH 7.4
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI