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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
6
hits in this display
Target
Integrin alpha-4/beta-1
(Homo sapiens (Human))
Novartis Institute For Biomedical Research
Curated by
ChEMBL
Ligand
BDBM50106086
((S)-3-(3,4-Dimethoxy-phenyl)-3-[2-((3-methoxy-prop...)
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Affinity Data
IC50: 7.10nM
Assay Description:
In vitro Very late antigen 4 cell adhesion inhibitory activity measured by binding of fluorescently labeled Ramos cells to immobilized VCAM-1.
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
antibodypedia
GoogleScholar
Ligand Info
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In Depth
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Article
PubMed
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Target
Integrin alpha-4/beta-1
(Homo sapiens (Human))
Novartis Institute For Biomedical Research
Curated by
ChEMBL
Ligand
BDBM50106086
((S)-3-(3,4-Dimethoxy-phenyl)-3-[2-((3-methoxy-prop...)
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Copy InChI
Affinity Data
IC50: 13nM
Assay Description:
Inhibition of fluorescent Ramos cell adhesion to fibronectin by Very late antigen 5 (VLA-5)
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Integrin alpha-4/beta-1
(Homo sapiens (Human))
Novartis Institute For Biomedical Research
Curated by
ChEMBL
Ligand
BDBM50106086
((S)-3-(3,4-Dimethoxy-phenyl)-3-[2-((3-methoxy-prop...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 22nM
Assay Description:
Inhibition of fluorescent Ramos cell adhesion to VCAM-1 by rat Very late antigen 4 (VLA-4) integrin
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Integrin alpha-4/beta-1
(Homo sapiens (Human))
Novartis Institute For Biomedical Research
Curated by
ChEMBL
Ligand
BDBM50106086
((S)-3-(3,4-Dimethoxy-phenyl)-3-[2-((3-methoxy-prop...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 27nM
Assay Description:
Inhibition of fluorescent Ramos cell adhesion to VCAM-1 by mouse Very late antigen 4 (VLA-4) integrin
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Integrin alpha-4/beta-7
(Homo sapiens (Human))
Novartis Institute For Biomedical Research
Curated by
ChEMBL
Ligand
BDBM50106086
((S)-3-(3,4-Dimethoxy-phenyl)-3-[2-((3-methoxy-prop...)
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Copy InChI
Affinity Data
IC50: >1.00E+5nM
Assay Description:
Inhibition of fluorescent Ramos cell adhesion to VCAM-1 by alpha4-beta7 integrin
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Integrin alpha-5/beta-1
(Homo sapiens (Human))
Novartis Institute For Biomedical Research
Curated by
ChEMBL
Ligand
BDBM50106086
((S)-3-(3,4-Dimethoxy-phenyl)-3-[2-((3-methoxy-prop...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >5.00E+5nM
Assay Description:
Inhibition of fluorescent Ramos cell adhesion to fibronectin by Very late antigen 4 (VLA-4)
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI