Home
About
Info
Download
WebServices
Contact
Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
16
hits in this display
Target
Matrix metalloproteinase-14
(Homo sapiens (Human))
Pfizer
Curated by
ChEMBL
Ligand
BDBM50343077
(CHEMBL1771212 | N-hydroxy-1-(2-methoxyethyl)-4-(4-...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 14nM
Assay Description:
Inhibition of human MMP-14
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
MMDB
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Matrilysin
(Homo sapiens (Human))
Pfizer
Curated by
ChEMBL
Ligand
BDBM50343077
(CHEMBL1771212 | N-hydroxy-1-(2-methoxyethyl)-4-(4-...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 7.00E+3nM
Assay Description:
Inhibition of human MMP-7
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
MMDB
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Interstitial collagenase
(Homo sapiens (Human))
Pfizer
Curated by
ChEMBL
Ligand
BDBM50343077
(CHEMBL1771212 | N-hydroxy-1-(2-methoxyethyl)-4-(4-...)
Copy SMILES
Copy InChI
Affinity Data
Ki: >1.00E+4nM
Assay Description:
Inhibition of human MMP-1
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
MMDB
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
72 kDa type IV collagenase
(Homo sapiens (Human))
Pfizer
Curated by
ChEMBL
Ligand
BDBM50343077
(CHEMBL1771212 | N-hydroxy-1-(2-methoxyethyl)-4-(4-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: <0.100nM
Assay Description:
Inhibition of human MMP-2
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
MMDB
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Collagenase 3
(Homo sapiens (Human))
Pfizer
Curated by
ChEMBL
Ligand
BDBM50343077
(CHEMBL1771212 | N-hydroxy-1-(2-methoxyethyl)-4-(4-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: <0.100nM
Assay Description:
Inhibition of human MMP-13
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
MMDB
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
MMDB
Copy BDB DOI
Target
72 kDa type IV collagenase
(Homo sapiens (Human))
Pfizer
Curated by
ChEMBL
Ligand
BDBM50343077
(CHEMBL1771212 | N-hydroxy-1-(2-methoxyethyl)-4-(4-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: <0.100nM
Assay Description:
Inhibition of human MMP2 assessed as cleavage of fluorogenic peptide MCAPro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 by fluorometric assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
MMDB
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Collagenase 3
(Homo sapiens (Human))
Pfizer
Curated by
ChEMBL
Ligand
BDBM50343077
(CHEMBL1771212 | N-hydroxy-1-(2-methoxyethyl)-4-(4-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: <0.100nM
Assay Description:
Inhibition of human MMP13 assessed as cleavage of fluorogenic peptide MCAPro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 by fluorometric assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
MMDB
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
MMDB
Copy BDB DOI
Target
Matrix metalloproteinase-9
(Homo sapiens (Human))
Pfizer
Curated by
ChEMBL
Ligand
BDBM50343077
(CHEMBL1771212 | N-hydroxy-1-(2-methoxyethyl)-4-(4-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 0.180nM
Assay Description:
Inhibition of human MMP9 assessed as cleavage of fluorogenic peptide MCAPro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 by fluorometric assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
MMDB
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Matrix metalloproteinase-9
(Homo sapiens (Human))
Pfizer
Curated by
ChEMBL
Ligand
BDBM50343077
(CHEMBL1771212 | N-hydroxy-1-(2-methoxyethyl)-4-(4-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 0.200nM
Assay Description:
Inhibition of human MMP-9
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
MMDB
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Neutrophil collagenase
(Homo sapiens (Human))
Pfizer
Curated by
ChEMBL
Ligand
BDBM50343077
(CHEMBL1771212 | N-hydroxy-1-(2-methoxyethyl)-4-(4-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.70nM
Assay Description:
Inhibition of human MMP-8
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
MMDB
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Neutrophil collagenase
(Homo sapiens (Human))
Pfizer
Curated by
ChEMBL
Ligand
BDBM50343077
(CHEMBL1771212 | N-hydroxy-1-(2-methoxyethyl)-4-(4-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.70nM
Assay Description:
Inhibition of human MMP8 assessed as cleavage of fluorogenic peptide MCAPro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 by fluorometric assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
MMDB
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Matrix metalloproteinase-14
(Homo sapiens (Human))
Pfizer
Curated by
ChEMBL
Ligand
BDBM50343077
(CHEMBL1771212 | N-hydroxy-1-(2-methoxyethyl)-4-(4-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 13nM
Assay Description:
Inhibition of human MMP14 assessed as cleavage of fluorogenic peptide MCAPro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 by fluorometric assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
MMDB
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Stromelysin-1
(Homo sapiens (Human))
Pfizer
Curated by
ChEMBL
Ligand
BDBM50343077
(CHEMBL1771212 | N-hydroxy-1-(2-methoxyethyl)-4-(4-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 29nM
Assay Description:
Inhibition of human MMP-3
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
MMDB
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Stromelysin-1
(Homo sapiens (Human))
Pfizer
Curated by
ChEMBL
Ligand
BDBM50343077
(CHEMBL1771212 | N-hydroxy-1-(2-methoxyethyl)-4-(4-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 29nM
Assay Description:
Inhibition of human MMP3 assessed as cleavage of fluorogenic peptide MCAPro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 by fluorometric assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
MMDB
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Matrilysin
(Homo sapiens (Human))
Pfizer
Curated by
ChEMBL
Ligand
BDBM50343077
(CHEMBL1771212 | N-hydroxy-1-(2-methoxyethyl)-4-(4-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 7.00E+3nM
Assay Description:
Inhibition of human MMP7 assessed as cleavage of fluorogenic peptide MCAPro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 by fluorometric assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
MMDB
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Interstitial collagenase
(Homo sapiens (Human))
Pfizer
Curated by
ChEMBL
Ligand
BDBM50343077
(CHEMBL1771212 | N-hydroxy-1-(2-methoxyethyl)-4-(4-...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of human MMP1 expressed in human HT-1080 cells assessed as cleavage of fluorogenic peptide MCAPro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 by fluoromet...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
MMDB
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI