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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
2
hits in this display
Target
Acetyl-CoA carboxylase 2
(Homo sapiens (Human))
Pfizer
US Patent
Ligand
BDBM152914
(US8993586, 111)
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Affinity Data
IC50: 3.30nM
Assay Description:
Preparation of rhACC2. Human ACC2 inhibition was measured using purified recombinant human ACC2 (hrACC2). Briefly, a full length Cytomax clone of ACC...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
US Patent
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Target
Acetyl-CoA carboxylase 1
(Homo sapiens (Human))
Pfizer
US Patent
Ligand
BDBM152914
(US8993586, 111)
Copy SMILES
Copy InChI
Affinity Data
IC50: 27nM
pH: 7.5
Assay Description:
Preparation of rhACC1. Two liters of SF9 cells, infected with recombinant baculovirus containing full length human ACC1 cDNA, were suspended in ice-c...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
US Patent
Copy BDB DOI