Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
University Of Regensburg

Curated by ChEMBL

LigandBDBM50428345(CHEMBL2331720)Copy SMILESCopy InChI

Affinity DataIC50:  237nMAssay Description:Inhibition of ABCG2 in human MCF7/Topo cells after 2 hrs by Hoechst 33342 microplate assayMore data for this Ligand-Target Pair

Target InfoPDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
DrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
University Of Regensburg

Curated by ChEMBL

LigandBDBM50428345(CHEMBL2331720)Copy SMILESCopy InChI

Affinity DataIC50:  1.80E+4nMAssay Description:Inhibition of ABCB1 in human KBV1 cells after 10 mins by Calcein-AM microplate assayMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
B.MOADantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI