Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
Novartis

US Patent

LigandBDBM136041(US8853203, 88h)Copy SMILESCopy InChI

Affinity DataIC50:  46nMAssay Description:Activity of compounds of the present invention was examined by determination to what extent the glutamate-induced elevation of the intracellular calc...More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPC cidPC sidSimilars

In DepthDetails US Patent
Copy BDB DOI

TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
Novartis

US Patent

LigandBDBM136041(US8853203, 88h)Copy SMILESCopy InChI

Affinity DataIC50:  1.05E+3nMAssay Description:Activity of compounds of the present invention was examined by determination to what extent the glutamate-induced elevation of the intracellular calc...More data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoPC cidPC sidSimilars

In DepthDetails US Patent
Copy BDB DOI