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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
11
hits in this display
Target
Nociceptin receptor
(Homo sapiens (Human))
Organon Laboratories
Curated by
ChEMBL
Ligand
BDBM50478166
(CHEMBL260768)
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Affinity Data
Ki: 2nM
Assay Description:
Displacement of [3H]nociceptin from human NOP receptor expressed in CHO cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Nociceptin receptor
(Homo sapiens (Human))
Organon Laboratories
Curated by
ChEMBL
Ligand
BDBM50200595
((+)-1-(2-methoxy-ethyl)-3-{1-[3-(5-methoxy-2-methy...)
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Affinity Data
Ki: 4.10nM
Assay Description:
Displacement of [3H]nociceptin from human NOP receptor expressed in CHO cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Mu-type opioid receptor
(Homo sapiens (Human))
Organon Laboratories
Curated by
ChEMBL
Ligand
BDBM50200595
((+)-1-(2-methoxy-ethyl)-3-{1-[3-(5-methoxy-2-methy...)
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Affinity Data
Ki: 186nM
Assay Description:
Displacement of [3H]Diprenorphine from human mu opioid receptor expressed in CHO cells
More data for this Ligand-Target Pair
Target Info
PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Mu-type opioid receptor
(Homo sapiens (Human))
Organon Laboratories
Curated by
ChEMBL
Ligand
BDBM50200595
((+)-1-(2-methoxy-ethyl)-3-{1-[3-(5-methoxy-2-methy...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 273nM
Assay Description:
Displacement of [3H]diprenorphine from human MOP receptor expressed in CHOK1 cells
More data for this Ligand-Target Pair
Target Info
PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Mu-type opioid receptor
(Homo sapiens (Human))
Organon Laboratories
Curated by
ChEMBL
Ligand
BDBM50200595
((+)-1-(2-methoxy-ethyl)-3-{1-[3-(5-methoxy-2-methy...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 273nM
Assay Description:
Displacement of [3H]diprenorphine from human MOP receptor expressed in CHOK1 cells
More data for this Ligand-Target Pair
Target Info
PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Nociceptin receptor
(Homo sapiens (Human))
Organon Laboratories
Curated by
ChEMBL
Ligand
BDBM50200595
((+)-1-(2-methoxy-ethyl)-3-{1-[3-(5-methoxy-2-methy...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 375nM
Assay Description:
Displacement of [3H]nociceptin from human NOP receptor expressed in CHO cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Kappa-type opioid receptor
(Cavia porcellus (domestic guinea pig))
Organon Laboratories
Curated by
ChEMBL
Ligand
BDBM50200595
((+)-1-(2-methoxy-ethyl)-3-{1-[3-(5-methoxy-2-methy...)
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Copy InChI
Affinity Data
Ki: 394nM
Assay Description:
Displacement of [3H]U-69593 from KOP receptor in guinea pig cortical tissue
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Kappa-type opioid receptor
(Cavia porcellus (domestic guinea pig))
Organon Laboratories
Curated by
ChEMBL
Ligand
BDBM50200595
((+)-1-(2-methoxy-ethyl)-3-{1-[3-(5-methoxy-2-methy...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 394nM
Assay Description:
Displacement of [3H]U-69593 from KOP receptor in guinea pig cortical tissue
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Delta-type opioid receptor
(Homo sapiens (Human))
Organon Laboratories
Curated by
ChEMBL
Ligand
BDBM50200595
((+)-1-(2-methoxy-ethyl)-3-{1-[3-(5-methoxy-2-methy...)
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Affinity Data
Ki: 2.16E+3nM
Assay Description:
Displacement of [3H]naltrindole from human DOP receptor expressed in deltaC6 cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Nociceptin receptor
(Homo sapiens (Human))
Organon Laboratories
Curated by
ChEMBL
Ligand
BDBM50200595
((+)-1-(2-methoxy-ethyl)-3-{1-[3-(5-methoxy-2-methy...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 24nM
Assay Description:
Agonist activity at human NOP receptor expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP production after 2 hrs
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Nociceptin receptor
(Homo sapiens (Human))
Organon Laboratories
Curated by
ChEMBL
Ligand
BDBM50200595
((+)-1-(2-methoxy-ethyl)-3-{1-[3-(5-methoxy-2-methy...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 24nM
Assay Description:
Agonist activity at human NOP receptor expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP production after 2 hrs
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI