Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 11 hits in this display   

TargetNociceptin receptor(Homo sapiens (Human))
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50478166(CHEMBL260768)
Affinity DataKi:  2nMAssay Description:Displacement of [3H]nociceptin from human NOP receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50200595((+)-1-(2-methoxy-ethyl)-3-{1-[3-(5-methoxy-2-methy...)
Affinity DataKi:  4.10nMAssay Description:Displacement of [3H]nociceptin from human NOP receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50200595((+)-1-(2-methoxy-ethyl)-3-{1-[3-(5-methoxy-2-methy...)
Affinity DataKi:  186nMAssay Description:Displacement of [3H]Diprenorphine from human mu opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50200595((+)-1-(2-methoxy-ethyl)-3-{1-[3-(5-methoxy-2-methy...)
Affinity DataKi:  273nMAssay Description:Displacement of [3H]diprenorphine from human MOP receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50200595((+)-1-(2-methoxy-ethyl)-3-{1-[3-(5-methoxy-2-methy...)
Affinity DataKi:  273nMAssay Description:Displacement of [3H]diprenorphine from human MOP receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50200595((+)-1-(2-methoxy-ethyl)-3-{1-[3-(5-methoxy-2-methy...)
Affinity DataKi:  375nMAssay Description:Displacement of [3H]nociceptin from human NOP receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50200595((+)-1-(2-methoxy-ethyl)-3-{1-[3-(5-methoxy-2-methy...)
Affinity DataKi:  394nMAssay Description:Displacement of [3H]U-69593 from KOP receptor in guinea pig cortical tissueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50200595((+)-1-(2-methoxy-ethyl)-3-{1-[3-(5-methoxy-2-methy...)
Affinity DataKi:  394nMAssay Description:Displacement of [3H]U-69593 from KOP receptor in guinea pig cortical tissueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50200595((+)-1-(2-methoxy-ethyl)-3-{1-[3-(5-methoxy-2-methy...)
Affinity DataKi:  2.16E+3nMAssay Description:Displacement of [3H]naltrindole from human DOP receptor expressed in deltaC6 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50200595((+)-1-(2-methoxy-ethyl)-3-{1-[3-(5-methoxy-2-methy...)
Affinity DataIC50:  24nMAssay Description:Agonist activity at human NOP receptor expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP production after 2 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Organon Laboratories

Curated by ChEMBL
LigandPNGBDBM50200595((+)-1-(2-methoxy-ethyl)-3-{1-[3-(5-methoxy-2-methy...)
Affinity DataIC50:  24nMAssay Description:Agonist activity at human NOP receptor expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP production after 2 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed