Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
University Court of The University of St Andrews

US Patent

LigandBDBM235915(US9365508, D3 (3-Cl, 4-OMe,)Copy SMILESCopy InChI

Affinity DataIC50:  1.07E+4nMAssay Description:All compounds were tested for inhibition of SIRT1 and SIRT2 using human recombinant enzymes available in the Fluor de Lys fluorescence-based assay ki...More data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADantibodypediaGoogleScholar

Ligand InfoPurchasePC cidPC sid

In DepthDetails US Patent
Copy BDB DOI

TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
University Court of The University of St Andrews

US Patent

LigandBDBM235915(US9365508, D3 (3-Cl, 4-OMe,)Copy SMILESCopy InChI

Affinity DataIC50:  6.25E+4nMAssay Description:All compounds were tested for inhibition of SIRT1 and SIRT2 using human recombinant enzymes available in the Fluor de Lys fluorescence-based assay ki...More data for this Ligand-Target Pair

Target InfoPDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADantibodypediaGoogleScholar

Ligand InfoPurchasePC cidPC sid

In DepthDetails US Patent
Copy BDB DOI