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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 9 hits in this display   

TargetMitogen-activated protein kinase 9(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50277623(CHEMBL451523 | N-(5-tert-butyl-2-methoxy-3-(3-(4-(...)
Affinity DataIC50:  3nMAssay Description:Inhibition of JNK2alpha2 (unknown origin) by by exchange curve binding kinetic analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50277623(CHEMBL451523 | N-(5-tert-butyl-2-methoxy-3-(3-(4-(...)
Affinity DataIC50:  480nMAssay Description:Inhibition of Abl (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50277623(CHEMBL451523 | N-(5-tert-butyl-2-methoxy-3-(3-(4-(...)
Affinity DataIC50:  880nMAssay Description:Inhibition of craf (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lyn(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50277623(CHEMBL451523 | N-(5-tert-butyl-2-methoxy-3-(3-(4-(...)
Affinity DataIC50:  2.40E+3nMAssay Description:Inhibition of Lyn (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-A receptor 3(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50277623(CHEMBL451523 | N-(5-tert-butyl-2-methoxy-3-(3-(4-(...)
Affinity DataIC50:  3.20E+3nMAssay Description:Inhibition of HEK (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-A receptor 2(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50277623(CHEMBL451523 | N-(5-tert-butyl-2-methoxy-3-(3-(4-(...)
Affinity DataIC50:  5.20E+3nMAssay Description:Inhibition of ECK (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50277623(CHEMBL451523 | N-(5-tert-butyl-2-methoxy-3-(3-(4-(...)
Affinity DataIC50:  5.40E+3nMAssay Description:Inhibition of EGFR (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50277623(CHEMBL451523 | N-(5-tert-butyl-2-methoxy-3-(3-(4-(...)
Affinity DataIC50:  6.40E+3nMAssay Description:Inhibition of PKBalpha/Akt1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50277623(CHEMBL451523 | N-(5-tert-butyl-2-methoxy-3-(3-(4-(...)
Affinity DataIC50:  7.20E+3nMAssay Description:Inhibition of bRaf (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed