Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Jena

Curated by ChEMBL
LigandPNGBDBM50020583(CHEMBL3290439)
Affinity DataIC50:  2.30E+3nMAssay Description:Inhibition of human recombinant 5-LO expressed in Escherichia coli Bl21 (DE3) using arachidonic acid as substrate preincubated for 10 mins measured a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Jena

Curated by ChEMBL
LigandPNGBDBM50020583(CHEMBL3290439)
Affinity DataIC50:  9.90E+3nMAssay Description:Inhibition of 5-LO in human neutrophils using arachidonic acid as substrate preincubated for 15 mins measured after 10 mins by HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSignal transducer and activator of transcription 3(Homo sapiens (Human))
University Jena

Curated by ChEMBL
LigandPNGBDBM50020583(CHEMBL3290439)
Affinity DataIC50:  3.57E+4nMAssay Description:Inhibition of STAT3 transcriptional activity in human HaCaT cells after 6 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed