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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
4
hits in this display
Target
Broad substrate specificity ATP-binding cassette transporter ABCG2
(Homo sapiens (Human))
University Bayreuth
Curated by
ChEMBL
Ligand
BDBM50195543
(CHEMBL2236206)
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Affinity Data
IC50: 2.40E+3nM
Assay Description:
Inhibition of BCRP in human MCF7/Topo cells assessed as mitoxantrone accumulation preincubated for 10 mins followed by mitoxantrone addition measured...
More data for this Ligand-Target Pair
Target Info
PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
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CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Trophozoite cysteine proteinase
(Plasmodium falciparum)
TBA
Ligand
BDBM50195543
(CHEMBL2236206)
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Affinity Data
IC50: 6.00E+3nM
Assay Description:
Inhibition of Plasmodium falciparum W2 cysteine protease
More data for this Ligand-Target Pair
Target Info
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
Copy BDB DOI
Target
Trophozoite cysteine proteinase
(Plasmodium falciparum)
TBA
Ligand
BDBM50195543
(CHEMBL2236206)
Copy SMILES
Copy InChI
Affinity Data
IC50: 6.00E+3nM
Assay Description:
Inhibition of Plasmodium falciparum W2 cysteine protease
More data for this Ligand-Target Pair
Target Info
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
Copy BDB DOI
Target
ATP-dependent translocase ABCB1
(Homo sapiens (Human))
University Bayreuth
Curated by
ChEMBL
Ligand
BDBM50195543
(CHEMBL2236206)
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Copy InChI
Affinity Data
IC50: 1.30E+4nM
Assay Description:
Inhibition of P-gp in human KB-V1/Vbl cells assessed as calcein-AM accumulation preincubated for 15 mins followed by calcein-AM addition measured aft...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI