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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 6 hits in this display   

TargetCarbonic anhydrase(Cryptococcus neoformans var. grubii (Filobasidiell...)
Griffith University

Curated by ChEMBL
LigandPNGBDBM50339592(2-amino-4-(4-hydroxy-3-methoxybenzylidene)-1H-imid...)
Affinity DataKi:  890nMAssay Description:Inhibition of Cryptococcus neoformans recombinant Can2 beta-carbonic anhydrase after 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase(Mycobacterium tuberculosis)
Griffith University

Curated by ChEMBL
LigandPNGBDBM50339592(2-amino-4-(4-hydroxy-3-methoxybenzylidene)-1H-imid...)
Affinity DataKi:  910nMAssay Description:Inhibition of Mycobacterium tuberculosis recombinant Rv3273 beta-carbonic anhydrase after 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase(Candida albicans (Yeast))
Griffith University

Curated by ChEMBL
LigandPNGBDBM50339592(2-amino-4-(4-hydroxy-3-methoxybenzylidene)-1H-imid...)
Affinity DataKi:  920nMAssay Description:Inhibition of Candida albicans recombinant Nce103 beta-carbonic anhydrase after 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Griffith University

Curated by ChEMBL
LigandPNGBDBM50339592(2-amino-4-(4-hydroxy-3-methoxybenzylidene)-1H-imid...)
Affinity DataKi:  9.60E+3nMAssay Description:Inhibition of human recombinant alpha-carbonic anhydrase 2 after 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Griffith University

Curated by ChEMBL
LigandPNGBDBM50339592(2-amino-4-(4-hydroxy-3-methoxybenzylidene)-1H-imid...)
Affinity DataKi:  1.05E+4nMAssay Description:Inhibition of human recombinant alpha-carbonic anhydrase 1 after 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-carbonic anhydrase 1(Mycobacterium tuberculosis)
Griffith University

Curated by ChEMBL
LigandPNGBDBM50339592(2-amino-4-(4-hydroxy-3-methoxybenzylidene)-1H-imid...)
Affinity DataKi:  1.18E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis recombinant Rv1284 beta-carbonic anhydrase after 15 mins by stopped flow CO2 hydration assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed