Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 10 hits in this display   

TargetMelanocortin receptor 4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50190978((R)-1-(4-(2-((S)-1-amino-3-methylbutyl)-4-(trifluo...)
Affinity DataKi:  6.5nMAssay Description:Displacement of [125I]NDP-MSH from human MC4R stably expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50190976((1S)-[2-{4-[2-methyl-3-(2-methoxy-4-chlorophenyl)p...)
Affinity DataKi:  14nMAssay Description:Displacement of [125I]NDP-MSH from human MC4R stably expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50190976((1S)-[2-{4-[2-methyl-3-(2-methoxy-4-chlorophenyl)p...)
Affinity DataKi:  14nMAssay Description:Displacement of [125I]NDPMSH from human MC4R expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50191018((S)-1-(4-(2-((S)-1-amino-3-methylbutyl)-4-(trifluo...)
Affinity DataKi:  31nMAssay Description:Displacement of [125I]NDP-MSH from human MC4R stably expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 5(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50190976((1S)-[2-{4-[2-methyl-3-(2-methoxy-4-chlorophenyl)p...)
Affinity DataKi:  86nMAssay Description:Displacement of [125I]NDP-MSH from human MC5R stably expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 5(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50190976((1S)-[2-{4-[2-methyl-3-(2-methoxy-4-chlorophenyl)p...)
Affinity DataKi:  86nMAssay Description:Displacement of [125I]NDPMSH from human MC5R expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 3(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50190976((1S)-[2-{4-[2-methyl-3-(2-methoxy-4-chlorophenyl)p...)
Affinity DataKi:  320nMAssay Description:Displacement of [125I]NDPMSH from human MC3R expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 3(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50190976((1S)-[2-{4-[2-methyl-3-(2-methoxy-4-chlorophenyl)p...)
Affinity DataKi:  320nMAssay Description:Displacement of [125I]NDP-MSH from human MC3R stably expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50190976((1S)-[2-{4-[2-methyl-3-(2-methoxy-4-chlorophenyl)p...)
Affinity DataIC50:  1.70E+3nMAssay Description:Activity at MC4R assessed as inhibition of alpha MSH-stimulated cAMP production in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50190976((1S)-[2-{4-[2-methyl-3-(2-methoxy-4-chlorophenyl)p...)
Affinity DataIC50:  1.70E+3nMAssay Description:Displacement of [125I]NDPMSH from human MC4R expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed