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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
10
hits in this display
Target
Melanocortin receptor 4
(Homo sapiens (Human))
Neurocrine Biosciences
Curated by
ChEMBL
Ligand
BDBM50190978
((R)-1-(4-(2-((S)-1-amino-3-methylbutyl)-4-(trifluo...)
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Affinity Data
Ki: 6.5nM
Assay Description:
Displacement of [125I]NDP-MSH from human MC4R stably expressed in HEK293 cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Melanocortin receptor 4
(Homo sapiens (Human))
Neurocrine Biosciences
Curated by
ChEMBL
Ligand
BDBM50190976
((1S)-[2-{4-[2-methyl-3-(2-methoxy-4-chlorophenyl)p...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 14nM
Assay Description:
Displacement of [125I]NDP-MSH from human MC4R stably expressed in HEK293 cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Melanocortin receptor 4
(Homo sapiens (Human))
Neurocrine Biosciences
Curated by
ChEMBL
Ligand
BDBM50190976
((1S)-[2-{4-[2-methyl-3-(2-methoxy-4-chlorophenyl)p...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 14nM
Assay Description:
Displacement of [125I]NDPMSH from human MC4R expressed in HEK293 cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Melanocortin receptor 4
(Homo sapiens (Human))
Neurocrine Biosciences
Curated by
ChEMBL
Ligand
BDBM50191018
((S)-1-(4-(2-((S)-1-amino-3-methylbutyl)-4-(trifluo...)
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Copy InChI
Affinity Data
Ki: 31nM
Assay Description:
Displacement of [125I]NDP-MSH from human MC4R stably expressed in HEK293 cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Melanocortin receptor 5
(Homo sapiens (Human))
Neurocrine Biosciences
Curated by
ChEMBL
Ligand
BDBM50190976
((1S)-[2-{4-[2-methyl-3-(2-methoxy-4-chlorophenyl)p...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 86nM
Assay Description:
Displacement of [125I]NDP-MSH from human MC5R stably expressed in HEK293 cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Melanocortin receptor 5
(Homo sapiens (Human))
Neurocrine Biosciences
Curated by
ChEMBL
Ligand
BDBM50190976
((1S)-[2-{4-[2-methyl-3-(2-methoxy-4-chlorophenyl)p...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 86nM
Assay Description:
Displacement of [125I]NDPMSH from human MC5R expressed in HEK293 cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Melanocortin receptor 3
(Homo sapiens (Human))
Neurocrine Biosciences
Curated by
ChEMBL
Ligand
BDBM50190976
((1S)-[2-{4-[2-methyl-3-(2-methoxy-4-chlorophenyl)p...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 320nM
Assay Description:
Displacement of [125I]NDPMSH from human MC3R expressed in HEK293 cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Melanocortin receptor 3
(Homo sapiens (Human))
Neurocrine Biosciences
Curated by
ChEMBL
Ligand
BDBM50190976
((1S)-[2-{4-[2-methyl-3-(2-methoxy-4-chlorophenyl)p...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 320nM
Assay Description:
Displacement of [125I]NDP-MSH from human MC3R stably expressed in HEK293 cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Melanocortin receptor 4
(Homo sapiens (Human))
Neurocrine Biosciences
Curated by
ChEMBL
Ligand
BDBM50190976
((1S)-[2-{4-[2-methyl-3-(2-methoxy-4-chlorophenyl)p...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.70E+3nM
Assay Description:
Activity at MC4R assessed as inhibition of alpha MSH-stimulated cAMP production in HEK293 cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Melanocortin receptor 4
(Homo sapiens (Human))
Neurocrine Biosciences
Curated by
ChEMBL
Ligand
BDBM50190976
((1S)-[2-{4-[2-methyl-3-(2-methoxy-4-chlorophenyl)p...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.70E+3nM
Assay Description:
Displacement of [125I]NDPMSH from human MC4R expressed in HEK293 cells
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI