Compile Data Set for Download or QSAR
maximum 50k data

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 6 hits in this display   

TargetMu-type opioid receptor(Homo sapiens (Human))
Sepracor

Curated by ChEMBL
LigandPNGBDBM50301919(4-amino-5-chloro-N-(2-((((1R,2R)-2-hydroxy-2-(3-hy...)
Affinity DataIC50:  190nMAssay Description:Binding affinity to human mu opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Sepracor

Curated by ChEMBL
LigandPNGBDBM50301919(4-amino-5-chloro-N-(2-((((1R,2R)-2-hydroxy-2-(3-hy...)
Affinity DataIC50:  340nMAssay Description:Binding affinity to human mu opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
Sepracor

Curated by ChEMBL
LigandPNGBDBM50301919(4-amino-5-chloro-N-(2-((((1R,2R)-2-hydroxy-2-(3-hy...)
Affinity DataIC50:  2.80E+3nMAssay Description:Displacement of [3H]granisetron from human recombinant 5-HT3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
Sepracor

Curated by ChEMBL
LigandPNGBDBM50301919(4-amino-5-chloro-N-(2-((((1R,2R)-2-hydroxy-2-(3-hy...)
Affinity DataIC50:  3.10E+3nMAssay Description:Displacement of [3H]granisetron from human recombinant 5-HT3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Sepracor

Curated by ChEMBL
LigandPNGBDBM50301919(4-amino-5-chloro-N-(2-((((1R,2R)-2-hydroxy-2-(3-hy...)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [3H]GR-113808 from human recombinant 5-HT4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 4(Homo sapiens (Human))
Sepracor

Curated by ChEMBL
LigandPNGBDBM50301919(4-amino-5-chloro-N-(2-((((1R,2R)-2-hydroxy-2-(3-hy...)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [3H]GR-113808 from human recombinant 5-HT4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed