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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

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TargetSerine/threonine-protein kinase B-raf [V600E](Homo sapiens (Human))
Cancer Research Uk Centre For Cancer Therapeutics

LigandPNGBDBM25578(2,6-Disubstituted Pyrazine, 24 | 2-N-(3-fluorophen...)
Affinity DataIC50:  1.20E+4nMpH: 7.2 T: 2°CAssay Description:BRAF kinase activity was quantified using a DELFIA-based MEK1 phosphorylation assay. IC50 values were derived from the sigmoidal dose-response curves...More data for this Ligand-Target Pair
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