Compile Data Set for Download or QSAR
maximum 50k data

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 7 hits in this display   

TargetLysine--tRNA ligase(Homo sapiens (Human))
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50249539(5-((1S,2R)-2-aminocyclohexylamino)-7-(3,5-dimethox...)
Affinity DataIC50:  4nMAssay Description:Inhibition of human SykMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50249539(5-((1S,2R)-2-aminocyclohexylamino)-7-(3,5-dimethox...)
Affinity DataIC50:  4nMAssay Description:Inhibition of human Syk expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50249539(5-((1S,2R)-2-aminocyclohexylamino)-7-(3,5-dimethox...)
Affinity DataIC50:  4nMAssay Description:Inhibition of recombinant Syk (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50249539(5-((1S,2R)-2-aminocyclohexylamino)-7-(3,5-dimethox...)
Affinity DataIC50:  330nMAssay Description:Inhibition of human ZAP70 expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50249539(5-((1S,2R)-2-aminocyclohexylamino)-7-(3,5-dimethox...)
Affinity DataIC50:  330nMAssay Description:Inhibition of human ZAP70More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50249539(5-((1S,2R)-2-aminocyclohexylamino)-7-(3,5-dimethox...)
Affinity DataIC50:  590nMAssay Description:Inhibition of Lck (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C beta type(Homo sapiens (Human))
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50249539(5-((1S,2R)-2-aminocyclohexylamino)-7-(3,5-dimethox...)
Affinity DataIC50:  2.66E+3nMAssay Description:Inhibition of PKCbeta2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed