Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Amgen

Curated by ChEMBL

LigandBDBM50382648(CHEMBL2024001)Copy SMILESCopy InChI

Affinity DataIC50:  28nMAssay Description:Inhibition of ALK phosphorylation in human Karpas-299 cells after 1 hrMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetALK tyrosine kinase receptor(Homo sapiens (Human))
Amgen

Curated by ChEMBL

LigandBDBM50382648(CHEMBL2024001)Copy SMILESCopy InChI

Affinity DataIC50:  31nMAssay Description:Inhibition of human N-terminal GST-fused ALK cytoplasmic domain (1058 to 1620) expressed in SF9 cells using Biotin-Ahx- EQEDEPEGIYGVLF-OH as substrat...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI