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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
4
hits in this display
Target
Neuronal acetylcholine receptor subunit alpha-7
(Homo sapiens (Human))
Instituto De Qu£Mica M£Dica (Iqm-Csic)
Curated by
ChEMBL
Ligand
BDBM50374402
(CHEMBL257591 | PNU-120596)
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Affinity Data
EC50: 3.80E+3nM
Assay Description:
Positive allosteric modulation at human alpha7 nACHR expressed in Xenopus oocyte assessed as potentiation of 200 uM ACh-induced current at holding po...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
Purchase
CHEMBL
MCE
PC cid
PC sid
PDB
In Depth
Details
Article
PubMed
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Neuronal acetylcholine receptor subunit alpha-7
(Homo sapiens (Human))
Instituto De Qu£Mica M£Dica (Iqm-Csic)
Curated by
ChEMBL
Ligand
BDBM50374402
(CHEMBL257591 | PNU-120596)
Copy SMILES
Copy InChI
Affinity Data
EC50: 220nM
Assay Description:
Positive allosteric modulation of human alpha7 nAChR expressed in Xenopus laevis oocytes assessed as increase in Ach-induced current at -90 mV membra...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
Purchase
CHEMBL
MCE
PC cid
PC sid
PDB
In Depth
Details
Article
PubMed
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Neuronal acetylcholine receptor subunit alpha-7
(Homo sapiens (Human))
Instituto De Qu£Mica M£Dica (Iqm-Csic)
Curated by
ChEMBL
Ligand
BDBM50374402
(CHEMBL257591 | PNU-120596)
Copy SMILES
Copy InChI
Affinity Data
EC50: 158nM
Assay Description:
Positive allosteric modulator activity at human alpha7 nAChR expressed in rat GH4C1 assessed as calcium mobilization by FLIPR assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
Purchase
CHEMBL
MCE
PC cid
PC sid
PDB
In Depth
Details
Article
PubMed
PDB
3D Structure (crystal)
Copy BDB DOI
Target
Neuronal acetylcholine receptor subunit alpha-7
(Homo sapiens (Human))
Instituto De Qu£Mica M£Dica (Iqm-Csic)
Curated by
ChEMBL
Ligand
BDBM50374402
(CHEMBL257591 | PNU-120596)
Copy SMILES
Copy InChI
Affinity Data
EC50: 1.50E+3nM
Assay Description:
Activity at human alpha-7 nACh receptor expressed in Xenopus laevis oocyte assessed as increase in acetylcholine-induced current
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
Purchase
CHEMBL
MCE
PC cid
PC sid
PDB
In Depth
Details
Article
PubMed
PDB
3D Structure (crystal)
Copy BDB DOI