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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
7
hits in this display
Target
ATP-dependent translocase ABCB1
(Homo sapiens (Human))
The Hong Kong Polytechnic University
Curated by
ChEMBL
Ligand
BDBM50091264
(CHEMBL3582155)
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Affinity Data
IC50: 3nM
Assay Description:
Modulation of P-gp (unknown origin) transfected in human MDA435/LCC6MDR cells assessed as reversible of paclitaxel resistance measured as IC50 for pa...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Broad substrate specificity ATP-binding cassette transporter ABCG2
(Homo sapiens (Human))
The Hong Kong Polytechnic University
Curated by
ChEMBL
Ligand
BDBM50091264
(CHEMBL3582155)
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Affinity Data
IC50: 176nM
Assay Description:
Modulation of BCRP (unknown origin) transfected in human HEK293/R2 cells assessed as potentiation of topotecan-induced cytotoxicity measured as topot...
More data for this Ligand-Target Pair
Target Info
PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Multidrug resistance-associated protein 1
(Homo sapiens (Human))
The Hong Kong Polytechnic University
Curated by
ChEMBL
Ligand
BDBM50091264
(CHEMBL3582155)
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Affinity Data
IC50: 434nM
Assay Description:
Modulation of MRP1 (unknown origin) transfected in human 2008/MRP1 cells assessed as potentiation of doxorubicin-induced cytotoxicity measured as dox...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
ATP-dependent translocase ABCB1
(Homo sapiens (Human))
The Hong Kong Polytechnic University
Curated by
ChEMBL
Ligand
BDBM50091264
(CHEMBL3582155)
Copy SMILES
Copy InChI
Affinity Data
EC50: 159nM
Assay Description:
Modulation of P-gp (unknown origin) transfected in human MDA435/LCC6MDR cells assessed as reversing paclitaxel resistance measured as cell survival a...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
ATP-dependent translocase ABCB1
(Homo sapiens (Human))
The Hong Kong Polytechnic University
Curated by
ChEMBL
Ligand
BDBM50091264
(CHEMBL3582155)
Copy SMILES
Copy InChI
Affinity Data
EC50: 193nM
Assay Description:
Modulation of P-gp (unknown origin) transfected in human MDA435/LCC6MDR cells assessed as reversing vinblastine resistance measured as cell survival ...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
ATP-dependent translocase ABCB1
(Homo sapiens (Human))
The Hong Kong Polytechnic University
Curated by
ChEMBL
Ligand
BDBM50091264
(CHEMBL3582155)
Copy SMILES
Copy InChI
Affinity Data
EC50: 139nM
Assay Description:
Modulation of P-gp (unknown origin) transfected in human MDA435/LCC6MDR cells assessed as reversing doxorubicin resistance measured as cell survival ...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
ATP-dependent translocase ABCB1
(Homo sapiens (Human))
The Hong Kong Polytechnic University
Curated by
ChEMBL
Ligand
BDBM50091264
(CHEMBL3582155)
Copy SMILES
Copy InChI
Affinity Data
EC50: 181nM
Assay Description:
Modulation of P-gp (unknown origin) transfected in human MDA435/LCC6MDR cells assessed as reversing vincristine resistance measured as cell survival ...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI