Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetMultidrug resistance-associated protein 1(Homo sapiens (Human))
University Of Regensburg

Curated by ChEMBL

LigandBDBM50139446(CHEMBL3763583)Copy SMILESCopy InChI

Affinity DataIC50:  6.80E+3nMAssay Description:Inhibition of human MRP1 transfected in MDCK2 cells assessed as inhibition of calcein-AM effluxMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidPatentsSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
University Of Regensburg

Curated by ChEMBL

LigandBDBM50139446(CHEMBL3763583)Copy SMILESCopy InChI

Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of ABCG2 in human MCF7/Topo cells by Hoechst 33342 assayMore data for this Ligand-Target Pair

Target InfoPDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
DrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidPatentsSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI