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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 8 hits in this display   

TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50106025((S)-2,2-Dimethyl-4-[4-(3,4,5-trimethoxy-phenoxy)-b...)
Affinity DataIC50:  1.5nMAssay Description:Inhibitory concentration against Tumor necrosis factor alpha converting enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50106025((S)-2,2-Dimethyl-4-[4-(3,4,5-trimethoxy-phenoxy)-b...)
Affinity DataIC50:  1.5nMAssay Description:Inhibition of TACE (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50106025((S)-2,2-Dimethyl-4-[4-(3,4,5-trimethoxy-phenoxy)-b...)
Affinity DataIC50:  1.60nMAssay Description:Inhibition of TACE (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50106025((S)-2,2-Dimethyl-4-[4-(3,4,5-trimethoxy-phenoxy)-b...)
Affinity DataIC50:  21nMAssay Description:Inhibition against Matrix metalloproteinase-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50106025((S)-2,2-Dimethyl-4-[4-(3,4,5-trimethoxy-phenoxy)-b...)
Affinity DataIC50:  26nMAssay Description:Inhibitory concentration against Matrix metalloproteinase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50106025((S)-2,2-Dimethyl-4-[4-(3,4,5-trimethoxy-phenoxy)-b...)
Affinity DataIC50:  501nMAssay Description:Inhibition of TACE (unknown origin) by cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50106025((S)-2,2-Dimethyl-4-[4-(3,4,5-trimethoxy-phenoxy)-b...)
Affinity DataIC50:  550nMAssay Description:Inhibition of TACE (unknown origin) by cell based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50106025((S)-2,2-Dimethyl-4-[4-(3,4,5-trimethoxy-phenoxy)-b...)
Affinity DataIC50:  550nMAssay Description:Concentration required to inhibit the release of tumor necrosis factor -alpha (TNF-alpha) in THP-1 cellular assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed