Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 6 hits in this display   

Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50038370(2-(2,5-Dimethoxy-4-trifluoromethyl-phenyl)-1-methy...)
Affinity DataKi:  2.20nMAssay Description:Binding affinity at cloned rat 5-hydroxytryptamine 2A receptor using [3H]-DOB as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Rattus norvegicus (Rat))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50038370(2-(2,5-Dimethoxy-4-trifluoromethyl-phenyl)-1-methy...)
Affinity DataKi:  3.78nMAssay Description:Binding affinity at cloned rat 5-hydroxytryptamine 2C receptor using [3H]-DOI as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50038370(2-(2,5-Dimethoxy-4-trifluoromethyl-phenyl)-1-methy...)
Affinity DataKi:  33nMAssay Description:Displacement of [3H]ketanserin from 5HT2A receptor in Sprague-Dawley rat brain by liquid scintillation spectroscopyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50038370(2-(2,5-Dimethoxy-4-trifluoromethyl-phenyl)-1-methy...)
Affinity DataKi:  2.23E+3nMAssay Description:Tested for the binding affinity against the site labelled by the 5-hydroxytryptamine 1A receptor agonist [3H]- 8-OH-DPATMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] A(Rattus norvegicus (rat))
Universidad De Chile

Curated by ChEMBL
LigandPNGBDBM50038370(2-(2,5-Dimethoxy-4-trifluoromethyl-phenyl)-1-methy...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibitory concentration against monoamine oxidase A in rat brain mitochondrial suspensionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Rattus norvegicus (rat))
Purdue University

Curated by ChEMBL
LigandPNGBDBM50038370(2-(2,5-Dimethoxy-4-trifluoromethyl-phenyl)-1-methy...)
Affinity DataEC50:  68.4nMAssay Description:Ability to stimulate phosphoinositide hydrolysis in NIH3T3 cells expressing the 5-hydroxytryptamine 2A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed