Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
Universit£

Curated by ChEMBL

LigandBDBM50363114(CHEMBL1945977)Copy SMILESCopy InChI

Affinity DataIC50:  3.25E+4nMAssay Description:Inhibition of human MDR1 expressed in MDCK cells assessed as calcein AM accumulation after 30 mins by fluorescence assayMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
B.MOADantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetMultidrug resistance-associated protein 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL

LigandBDBM50363114(CHEMBL1945977)Copy SMILESCopy InChI

Affinity DataIC50:  4.06E+4nMAssay Description:Inhibition of MRP1 expressed in MDCK cells assessed as calcein AM accumulation after 30 mins by fluorescence assayMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI