Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)
Found 18 hits in this display
BDBM102619(K02288a | US10688093, Compound 382_0087_0284 | US1...)
BDBM102619(K02288a | US10688093, Compound 382_0087_0284 | US1...)
BDBM102619(K02288a | US10688093, Compound 382_0087_0284 | US1...)
BDBM102619(K02288a | US10688093, Compound 382_0087_0284 | US1...)
BDBM102619(K02288a | US10688093, Compound 382_0087_0284 | US1...)
BDBM102619(K02288a | US10688093, Compound 382_0087_0284 | US1...)
BDBM102619(K02288a | US10688093, Compound 382_0087_0284 | US1...)
IC50: 35nMAssay Description:Inhibition of human recombinant human ALK2 kinase after 45 mins by liquid scintillation counting in presence of ATP [gamma-32P]More data for this Ligand-Target Pair
BDBM102619(K02288a | US10688093, Compound 382_0087_0284 | US1...)
IC50: 230nMAssay Description:Inhibition of BMP2-induced BMP receptor type 1 ALK2 in mouse C2C12 cells after 30 mins by luciferase reporter gene assayMore data for this Ligand-Target Pair
BDBM102619(K02288a | US10688093, Compound 382_0087_0284 | US1...)
BDBM102619(K02288a | US10688093, Compound 382_0087_0284 | US1...)
BDBM102619(K02288a | US10688093, Compound 382_0087_0284 | US1...)
BDBM102619(K02288a | US10688093, Compound 382_0087_0284 | US1...)
BDBM102619(K02288a | US10688093, Compound 382_0087_0284 | US1...)
IC50: 420nMAssay Description:Inhibition of BMP6-induced BMP receptor type 1 ALK2 in mouse C2C12 cells after 30 mins by luciferase reporter gene assayMore data for this Ligand-Target Pair
BDBM102619(K02288a | US10688093, Compound 382_0087_0284 | US1...)
BDBM102619(K02288a | US10688093, Compound 382_0087_0284 | US1...)
BDBM102619(K02288a | US10688093, Compound 382_0087_0284 | US1...)
IC50: 723nMAssay Description:The assay procedure determines the IC50 of each potential FYN kinase inhibitor by measuring the enzyme catalyzed ATP-dependent phosphorylation of the...More data for this Ligand-Target Pair
BDBM102619(K02288a | US10688093, Compound 382_0087_0284 | US1...)
IC50: 723nMAssay Description:The ADP-Glo Kinase Assay is specifically designed to quantify kinase activity by measuring the ADP produced in the reaction The reaction buffer...More data for this Ligand-Target Pair
BDBM102619(K02288a | US10688093, Compound 382_0087_0284 | US1...)
IC50: 3.40E+3nMAssay Description:Inhibition of TGFbeta1-induced TGFbeta type 1 ALK5 in HEK293T cells after 30 mins by luciferase reporter gene assayMore data for this Ligand-Target Pair