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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

TargetProstaglandin E synthase(Homo sapiens (Human))
University Of Salerno

Curated by ChEMBL
LigandPNGBDBM50386155(CHEMBL2042360)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of mPGES1 in IL-1beta-stimulated human A549 cell assessed as inhibition of PGE2 production preincubated for 15 mins before substrate addit...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Salerno

Curated by ChEMBL
LigandPNGBDBM50386155(CHEMBL2042360)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human recombinant 5-lipoxygenase in cell-free system preincubated for 10 mins before substrate arachidonic acid addition measured after...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of Salerno

Curated by ChEMBL
LigandPNGBDBM50386155(CHEMBL2042360)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of 5-lipoxygenase in human neutrophil preincubated for 15 mins before substrate arachidonic acid addition measured after 10 mins by HPLC m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed