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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
4
hits in this display
Target
Rho-associated protein kinase 2 [1-543,T431N]
(Homo sapiens (Human))
The Scripps Research Institute
Ligand
BDBM25473
(N-[2-methoxy-4-(1H-pyrazol-4-yl)phenyl]-2,3-dihydr...)
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Affinity Data
IC50: 3.30nM
pH: 7.0 T: 2°C
Assay Description:
Assays were performed using the STK2 kinase system from Cisbio. Reaction mixture containing STK2 substrate, ATP and test compound was added to the we...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
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Target
Serine/threonine-protein kinase MRCK alpha
(Homo sapiens (Human))
The Scripps Research Institute
Ligand
BDBM25473
(N-[2-methoxy-4-(1H-pyrazol-4-yl)phenyl]-2,3-dihydr...)
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Affinity Data
IC50: 367nM
pH: 7.3 T: 2°C
Assay Description:
The mixture of a S6-peptide, ATP, and test compound was added to the wells using a BioRAPTR FRD Workstation (Aurora Discovery). Reaction was started ...
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
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Target
cAMP-dependent protein kinase catalytic subunit alpha
(Homo sapiens (Human))
The Scripps Research Institute
Ligand
BDBM25473
(N-[2-methoxy-4-(1H-pyrazol-4-yl)phenyl]-2,3-dihydr...)
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Affinity Data
IC50: 940nM
pH: 7.3 T: 2°C
Assay Description:
Reaction mixture of kemptide, ATP, and test compound was added to the wells using a BioRAPTR FRD Workstation (Aurora Discovery). Reaction was started...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
RAC-alpha serine/threonine-protein kinase
(Homo sapiens (Human))
The Scripps Research Institute
Ligand
BDBM25473
(N-[2-methoxy-4-(1H-pyrazol-4-yl)phenyl]-2,3-dihydr...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 8.82E+3nM
pH: 7.3 T: 2°C
Assay Description:
The mixture of a S6-peptide, ATP, and test compound was added to the wells using a BioRAPTR FRD Workstation (Aurora Discovery). Reaction was started ...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI