Home
About
Info
Download
WebServices
Contact
Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
3
hits in this display
Target
Focal adhesion kinase 1
(Mus musculus (Mouse))
Cancer Therapeutics Crc
US Patent
Ligand
BDBM176588
(US9120761, 2)
Copy SMILES
Copy InChI
Affinity Data
IC50: 7.10nM
pH: 7.4
Assay Description:
A biotin labeled peptide is used as substrate (amino acid sequence: Biotin-Glu-Gly-Pro-Trp-Leu-Glu-Glu-Glu-Glu-Glu-Ala-Tyr-Gly-Trp-Met-Asp-Phe-NH2) S...
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
US Patent
Copy BDB DOI
Target
Vascular endothelial growth factor receptor 3 [818-948,1003-1077]
(Homo sapiens (Human))
Cancer Therapeutics Crc
US Patent
Ligand
BDBM176588
(US9120761, 2)
Copy SMILES
Copy InChI
Affinity Data
IC50: 3.69E+3nM
pH: 7.4
Assay Description:
Compounds of the invention may be tested for in vitro activity in the following assay: A biotin labeled peptide is used as substrate (amino acid sequ...
More data for this Ligand-Target Pair
Target Info
UniProtKB/SwissProt
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
US Patent
Copy BDB DOI
Target
Focal adhesion kinase 1
(Mus musculus (Mouse))
Cancer Therapeutics Crc
US Patent
Ligand
BDBM176588
(US9120761, 2)
Copy SMILES
Copy InChI
Affinity Data
Kd: 0.740nM
pH: 7.4
Assay Description:
In running buffer (0.01 M HEPES pH 7.4, 0.15 M NaCl, 0.005% Surfactant P20, mM MgCl2, and 1% DMSO)N-terminally GST-fused purified FAK enzyme was capt...
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
Ligand Info
PC cid
PC sid
Similars
In Depth
Details
US Patent
Copy BDB DOI