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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 11 hits in this display   

TargetCytochrome P450 1B1(Homo sapiens (Human))
University Of Shizuoka

Curated by ChEMBL
LigandPNGBDBM50241084(3'-Methoxyapigenin | 4',5,7-trihydroxy-3'-methoxyf...)
Affinity DataIC50:  20nMAssay Description:Inhibition of human CYP1B1 by EROD assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1B1(Homo sapiens (Human))
University Of Shizuoka

Curated by ChEMBL
LigandPNGBDBM50241084(3'-Methoxyapigenin | 4',5,7-trihydroxy-3'-methoxyf...)
Affinity DataIC50:  20nMAssay Description:Inhibition of recombinant human CYP1B1 expressed in supersomes using ethoxyresorufin as substrate preincubated for 5 mins followed by substrate addit...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50241084(3'-Methoxyapigenin | 4',5,7-trihydroxy-3'-methoxyf...)
Affinity DataIC50:  95nMAssay Description:Inhibition of recombinant human CYP1A1 expressed in supersomes using ethoxyresorufin as substrate preincubated for 5 mins followed by substrate addit...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50241084(3'-Methoxyapigenin | 4',5,7-trihydroxy-3'-methoxyf...)
Affinity DataIC50:  95nMAssay Description:Inhibition of human CYP1A1 by EROD assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
University Of Shizuoka

Curated by ChEMBL
LigandPNGBDBM50241084(3'-Methoxyapigenin | 4',5,7-trihydroxy-3'-methoxyf...)
Affinity DataIC50:  1.12E+3nMAssay Description:Inhibition of human CYP1A2 by EROD assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMultidrug resistance-associated protein 1(Homo sapiens (Human))
The Hong Kong Polytechnic University

Curated by ChEMBL
LigandPNGBDBM50241084(3'-Methoxyapigenin | 4',5,7-trihydroxy-3'-methoxyf...)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of MRP1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase B(Homo sapiens (Human))
Konkuk University

LigandPNGBDBM50241084(3'-Methoxyapigenin | 4',5,7-trihydroxy-3'-methoxyf...)
Affinity DataIC50:  3.98E+3nMAssay Description:The kinase assay was performed using the EMD Millipore KinaseProfiler service assay protocol. Aurora B kinase was supplied by EMD Millipore Corp. The...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetXanthine dehydrogenase/oxidase(Bos taurus (Bovine))
TBA

Curated by ChEMBL
LigandPNGBDBM50241084(3'-Methoxyapigenin | 4',5,7-trihydroxy-3'-methoxyf...)
Affinity DataIC50:  1.40E+4nMAssay Description:Inhibition of cow milk xanthine oxidaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Eberhard Karls University Of Tuebingen

LigandPNGBDBM50241084(3'-Methoxyapigenin | 4',5,7-trihydroxy-3'-methoxyf...)
Affinity DataIC50:  3.36E+4nMT: 2°CAssay Description:The p38alpha reaction was carried out by using kinase (12ng per well), ATP (100uM) and incubated for 60 min at 37 C. For the JNK3 assay, kinase (10n...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetATP-binding cassette sub-family C member 2(Homo sapiens (Human))
The Hong Kong Polytechnic University

Curated by ChEMBL
LigandPNGBDBM50241084(3'-Methoxyapigenin | 4',5,7-trihydroxy-3'-methoxyf...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of MRP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutathione S-transferase Mu 1(Homo sapiens (Human))
Nmmlsc

Curated by PubChem BioAssay
LigandPNGBDBM50241084(3'-Methoxyapigenin | 4',5,7-trihydroxy-3'-methoxyf...)
Affinity DataEC50:  1.75E+3nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-re...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay