Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Development Center For Biotechnology

US Patent
LigandPNGBDBM127082(US8785459, 157)
Affinity DataIC50:  26.8nMAssay Description:Inhibition of kinase activity by test compound disclosed herein was estimated by quantifying the amount of [33P] incorporation of substrate in the pr...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSerine/threonine-protein kinase B-raf [V600E](Homo sapiens (Human))
Development Center For Biotechnology

US Patent
LigandPNGBDBM127082(US8785459, 157)
Affinity DataIC50:  37.5nMAssay Description:Inhibition of kinase activity by test compound disclosed herein was estimated by quantifying the amount of [33P] incorporation of substrate in the pr...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Development Center For Biotechnology

US Patent
LigandPNGBDBM127082(US8785459, 157)
Affinity DataIC50:  161nMAssay Description:Inhibition of kinase activity by test compound disclosed herein was estimated by quantifying the amount of [33P] incorporation of substrate in the pr...More data for this Ligand-Target Pair
In DepthDetails US Patent