Home
About
Info
Download
WebServices
Contact
Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
2
hits in this display
Target
Leukotriene C4 synthase
(Homo sapiens (Human))
Astrazeneca
US Patent
Ligand
BDBM223258
(2-(5-((Cyclopropylmethyl)(2,3-difluoro-4-methylben...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 185nM
Assay Description:
In the assay, LTC4 synthase catalyses the reaction where the substrate LTA4 methyl ester is converted to LTC4 methyl ester.In order to obtain IC50-va...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI
Target
Leukotriene C4 synthase
(Homo sapiens (Human))
Astrazeneca
US Patent
Ligand
BDBM223258
(2-(5-((Cyclopropylmethyl)(2,3-difluoro-4-methylben...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 185nM
pH: 7.8
Assay Description:
In the assay, LTC4 synthase catalyses the reaction where the substrate LTA4 is converted to LTC4. Recombinant human LTC4 synthase is expressed in Pic...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
PC cid
PC sid
In Depth
Details
US Patent
Copy BDB DOI