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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
8
hits in this display
Target
Acetylcholinesterase
(Homo sapiens (Human))
Universit£
Curated by
ChEMBL
Ligand
BDBM50280646
(2-[1-(1-Benzyl-piperidin-4-yl)-meth-(E)-ylidene]-5...)
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Affinity Data
Ki: 35nM
Assay Description:
Non-competitive inhibition of human erythrocytes AchE using acetylthiocholine iodide as substrate incubated for 20 mins by Lineweaver-Burk plot analy...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
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GoogleScholar
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Target
Cholinesterase
(Equus caballus (Horse))
Universit£
Curated by
ChEMBL
Ligand
BDBM50280646
(2-[1-(1-Benzyl-piperidin-4-yl)-meth-(E)-ylidene]-5...)
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Affinity Data
Ki: 2.44E+3nM
Assay Description:
Mixed inhibition of horse serum BuChE using butyrylthiocoline iodide as substrate incubated for 20 mins by Lineweaver-Burk plot analysis
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Target Info
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Target
Acetylcholinesterase
(Mus musculus (mouse))
TBA
Curated by
ChEMBL
Ligand
BDBM50280646
(2-[1-(1-Benzyl-piperidin-4-yl)-meth-(E)-ylidene]-5...)
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Affinity Data
IC50: 13nM
Assay Description:
Inhibition of Acetylcholinesterase activity in mouse brain homogenate
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
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KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
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CHEMBL
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PDB
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Target
Acetylcholinesterase
(Homo sapiens (Human))
Universit£
Curated by
ChEMBL
Ligand
BDBM50280646
(2-[1-(1-Benzyl-piperidin-4-yl)-meth-(E)-ylidene]-5...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 58nM
Assay Description:
Inhibition of human erythrocytes AchE using acetylthiocholine iodide as substrate incubated for 20 mins by Ellman method
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
PDB
Patents
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In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Acetylcholinesterase
(Electrophorus electricus (Electric eel))
University Of Pretoria
Curated by
ChEMBL
Ligand
BDBM50280646
(2-[1-(1-Benzyl-piperidin-4-yl)-meth-(E)-ylidene]-5...)
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Affinity Data
IC50: 420nM
Assay Description:
Inhibition of electric eel AChE using acetylthiocholine iodide as substrate by Ellman's method
More data for this Ligand-Target Pair
Target Info
UniProtKB/SwissProt
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CHEMBL
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Article
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Target
Beta-secretase 1
(Homo sapiens (Human))
China Pharmaceutical University
Curated by
ChEMBL
Ligand
BDBM50280646
(2-[1-(1-Benzyl-piperidin-4-yl)-meth-(E)-ylidene]-5...)
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Affinity Data
IC50: 697nM
Assay Description:
Inhibition of BACE-1 (unknown origin)
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
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CHEMBL
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In Depth
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Article
PubMed
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Target
Beta-secretase 1
(Mus musculus (Mouse))
Universit£
Curated by
ChEMBL
Ligand
BDBM50280646
(2-[1-(1-Benzyl-piperidin-4-yl)-meth-(E)-ylidene]-5...)
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Affinity Data
IC50: <1.00E+3nM
Assay Description:
Inhibition of mouse BACE-1 preincubated for 10 mins followed by fluorescent peptide substrate addition measured for 30 mins by fluorescence plate rea...
More data for this Ligand-Target Pair
Target Info
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CHEMBL
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Article
PubMed
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Target
Cholinesterase
(Equus caballus (Horse))
Universit£
Curated by
ChEMBL
Ligand
BDBM50280646
(2-[1-(1-Benzyl-piperidin-4-yl)-meth-(E)-ylidene]-5...)
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Copy InChI
Affinity Data
IC50: 4.74E+3nM
Assay Description:
Inhibition of horse serum BuChE using butyrylthiocoline iodide as substrate incubated for 20 mins by Ellman method
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
PDB
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI