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Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
6
hits in this display
Target
Acetylcholinesterase
(Mus musculus (mouse))
TBA
Curated by
ChEMBL
Ligand
BDBM50029937
(5,6-Dimethoxy-2-[1-(4-methyl-benzyl)-piperidin-4-y...)
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Affinity Data
IC50: 40nM
Assay Description:
Inhibition of Acetylcholinesterase activity in mouse brain homogenate
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
Copy BDB DOI
Target
Acetylcholinesterase
(Mus musculus (mouse))
TBA
Curated by
ChEMBL
Ligand
BDBM50029937
(5,6-Dimethoxy-2-[1-(4-methyl-benzyl)-piperidin-4-y...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 40nM
Assay Description:
Inhibitory activity against acetylcholinesterase
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Acetylcholinesterase
(Homo sapiens (Human))
China Pharmaceutical University
Curated by
ChEMBL
Ligand
BDBM50029937
(5,6-Dimethoxy-2-[1-(4-methyl-benzyl)-piperidin-4-y...)
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Copy InChI
Affinity Data
IC50: 127nM
Assay Description:
Inhibition of human erythrocytes AChE using acetylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition measured up ...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Acetylcholinesterase
(Electrophorus electricus (Electric eel))
China Pharmaceutical University
Curated by
ChEMBL
Ligand
BDBM50029937
(5,6-Dimethoxy-2-[1-(4-methyl-benzyl)-piperidin-4-y...)
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Affinity Data
IC50: 221nM
Assay Description:
Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition measured up to 3 m...
More data for this Ligand-Target Pair
Target Info
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Cholinesterase
(Equus caballus (Horse))
China Pharmaceutical University
Curated by
ChEMBL
Ligand
BDBM50029937
(5,6-Dimethoxy-2-[1-(4-methyl-benzyl)-piperidin-4-y...)
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Affinity Data
IC50: 6.67E+3nM
Assay Description:
Inhibition of equine serum BuChE using s-butyrylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition measured up to...
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Cholinesterase
(Homo sapiens (Human))
China Pharmaceutical University
Curated by
ChEMBL
Ligand
BDBM50029937
(5,6-Dimethoxy-2-[1-(4-methyl-benzyl)-piperidin-4-y...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 4.38E+4nM
Assay Description:
Inhibition of human serum BuChE using s-butyrylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition measured up to ...
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI