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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
4
hits in this display
Target
5-hydroxytryptamine receptor 2C
(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50086072
(5-Methoxy-6-trifluoromethyl-2,3-dihydro-indole-1-c...)
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Affinity Data
Ki: 1nM
Assay Description:
Binding affinity towards human cloned 5-hydroxytryptamine receptor 2C in HEK293 cells, using [3H]mesulergine as radioligand.
Checked by Author
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
5-hydroxytryptamine receptor 2B
(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50086072
(5-Methoxy-6-trifluoromethyl-2,3-dihydro-indole-1-c...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 5nM
Assay Description:
Binding affinities towards human cloned 5-hydroxytryptamine 2B receptor in HEK293 cells using [3H]5-HT as radioligand.
Checked by Author
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
5-hydroxytryptamine receptor 2A
(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50086072
(5-Methoxy-6-trifluoromethyl-2,3-dihydro-indole-1-c...)
Copy SMILES
Copy InChI
Affinity Data
Ki: 5.01E+3nM
Assay Description:
Binding affinity towards human cloned 5-hydroxytryptamine receptor 2A in HEK293 cells, using [3H]ketanserin as radioligand.
Checked by Author
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Cytochrome P450 1A2
(Homo sapiens (Human))
Smithkline Beecham Pharmaceuticals
Curated by
ChEMBL
Ligand
BDBM50086072
(5-Methoxy-6-trifluoromethyl-2,3-dihydro-indole-1-c...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 7.00E+3nM
Assay Description:
Inhibition of heterologously expressed human cytochrome P450 1A2.
Checked by Author
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI