Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

TargetAlpha-2C adrenergic receptor(Homo sapiens (Human))
Janssen-Cilag

Curated by ChEMBL

LigandBDBM50146511(4-{(E)-3-[4-((3R,3aS)-7,8-Dimethoxy-3a,4-dihydro-3...)Copy SMILESCopy InChI

Affinity DataKi:  0.600nMAssay Description:In vitro binding affinity to human alpha-2C adrenergic receptorMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
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TargetAlpha-2A adrenergic receptor(Homo sapiens (Human))
Janssen-Cilag

Curated by ChEMBL

LigandBDBM50146511(4-{(E)-3-[4-((3R,3aS)-7,8-Dimethoxy-3a,4-dihydro-3...)Copy SMILESCopy InChI

Affinity DataKi:  1.90nMAssay Description:In vitro binding affinity to the human alpha-2A adrenergic receptorMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Janssen-Cilag

Curated by ChEMBL

LigandBDBM50146511(4-{(E)-3-[4-((3R,3aS)-7,8-Dimethoxy-3a,4-dihydro-3...)Copy SMILESCopy InChI

Affinity DataKi:  7.60nMAssay Description:In vitro binding affinity towards human serotonin transporterMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
DrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI