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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetAurora kinase B(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM26272(2-{3-[(7-{3-[4-(hydroxymethyl)piperidin-1-yl]propo...)
Affinity DataKi:  18nM ΔG°:  -43.8kJ/molepH: 7.5 T: 2°CAssay Description:In vitro kinase assay using recombinant Aurora B bound to INCENP was incubated at room temperature with substrate, and test compounds in the presence...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
Astrazeneca

LigandPNGBDBM26272(2-{3-[(7-{3-[4-(hydroxymethyl)piperidin-1-yl]propo...)
Affinity DataKi:  1.60E+3nM ΔG°:  -33.1kJ/moleT: 2°CAssay Description:In vitro kinase assay using recombinant Aurora A purified from Sf9 cells was incubated at room temperature with substrate, and test compounds in the ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed