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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
12
hits in this display
Target
Epidermal growth factor receptor
(Homo sapiens (Human))
4Sc
Curated by
ChEMBL
Ligand
BDBM50304196
(CHEMBL593860 | N-[4-(Benzo[d]thiazol-2''-yl)-3-hyd...)
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Affinity Data
IC50: 2nM
Assay Description:
Inhibition of wild type EGF-R by microplate scintillation counting
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Receptor tyrosine-protein kinase erbB-2
(Homo sapiens (Human))
4Sc
Curated by
ChEMBL
Ligand
BDBM50304196
(CHEMBL593860 | N-[4-(Benzo[d]thiazol-2''-yl)-3-hyd...)
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Affinity Data
IC50: 5nM
Assay Description:
Inhibition of ERBB2 by microplate scintillation counting
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Angiopoietin-1 receptor
(Homo sapiens (Human))
4Sc
Curated by
ChEMBL
Ligand
BDBM50304196
(CHEMBL593860 | N-[4-(Benzo[d]thiazol-2''-yl)-3-hyd...)
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Copy InChI
Affinity Data
IC50: 110nM
Assay Description:
Inhibition of TIE2 by microplate scintillation counting
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Aurora kinase A
(Homo sapiens (Human))
4Sc
Curated by
ChEMBL
Ligand
BDBM50304196
(CHEMBL593860 | N-[4-(Benzo[d]thiazol-2''-yl)-3-hyd...)
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Affinity Data
IC50: 120nM
Assay Description:
Inhibition of Aurora-A by microplate scintillation counting
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Aurora kinase B
(Homo sapiens (Human))
4Sc
Curated by
ChEMBL
Ligand
BDBM50304196
(CHEMBL593860 | N-[4-(Benzo[d]thiazol-2''-yl)-3-hyd...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 300nM
Assay Description:
Inhibition of Aurora-B by microplate scintillation counting
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human))
4Sc
Curated by
ChEMBL
Ligand
BDBM50304196
(CHEMBL593860 | N-[4-(Benzo[d]thiazol-2''-yl)-3-hyd...)
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Copy InChI
Affinity Data
IC50: 1.20E+3nM
Assay Description:
Inhibition of VEGFR2 by microplate scintillation counting
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Platelet-derived growth factor receptor beta
(Homo sapiens (Human))
4Sc
Curated by
ChEMBL
Ligand
BDBM50304196
(CHEMBL593860 | N-[4-(Benzo[d]thiazol-2''-yl)-3-hyd...)
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Affinity Data
IC50: 2.10E+3nM
Assay Description:
Inhibition of PDGFRbeta by microplate scintillation counting
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Vascular endothelial growth factor receptor 3
(Homo sapiens (Human))
4Sc
Curated by
ChEMBL
Ligand
BDBM50304196
(CHEMBL593860 | N-[4-(Benzo[d]thiazol-2''-yl)-3-hyd...)
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Affinity Data
IC50: 7.10E+3nM
Assay Description:
Inhibition of VEGFR3 by microplate scintillation counting
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Angiopoietin-1 receptor
(Homo sapiens (Human))
4Sc
Curated by
ChEMBL
Ligand
BDBM50304196
(CHEMBL593860 | N-[4-(Benzo[d]thiazol-2''-yl)-3-hyd...)
Copy SMILES
Copy InChI
Affinity Data
EC50: >1.00E+4nM
Assay Description:
Inhibition of TIE2 by microplate scintillation counting
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Aurora kinase B
(Homo sapiens (Human))
4Sc
Curated by
ChEMBL
Ligand
BDBM50304196
(CHEMBL593860 | N-[4-(Benzo[d]thiazol-2''-yl)-3-hyd...)
Copy SMILES
Copy InChI
Affinity Data
EC50: >1.00E+4nM
Assay Description:
Inhibition of Aurora-B in human HCT116 cells by cellular proliferation assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Vascular endothelial growth factor receptor 3
(Homo sapiens (Human))
4Sc
Curated by
ChEMBL
Ligand
BDBM50304196
(CHEMBL593860 | N-[4-(Benzo[d]thiazol-2''-yl)-3-hyd...)
Copy SMILES
Copy InChI
Affinity Data
EC50: >1.00E+4nM
Assay Description:
Inhibition of VEGFR3 in human HCT116 cells by cellular phosphorylation assay
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Epidermal growth factor receptor
(Homo sapiens (Human))
4Sc
Curated by
ChEMBL
Ligand
BDBM50304196
(CHEMBL593860 | N-[4-(Benzo[d]thiazol-2''-yl)-3-hyd...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 9.40E+3nM
Assay Description:
Inhibition of EGFR in human HCT116 cells by cellular phosphorylation assay
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI