Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 7 hits in this display   

TargetCytochrome P450 1A2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50148708(CHEMBL120067 | [4-(2,4-Difluoro-phenylamino)-pheny...)
Affinity DataIC50: >2.00E+3nMAssay Description:Inhibition of human cytochrome P450 1A2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50148708(CHEMBL120067 | [4-(2,4-Difluoro-phenylamino)-pheny...)
Affinity DataIC50: >2.00E+3nMAssay Description:Inhibition of human cytochrome P450 2D6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50148708(CHEMBL120067 | [4-(2,4-Difluoro-phenylamino)-pheny...)
Affinity DataIC50: >2.00E+3nMAssay Description:Inhibition of human cytochrome P450 3A4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50148708(CHEMBL120067 | [4-(2,4-Difluoro-phenylamino)-pheny...)
Affinity DataIC50: >2.00E+3nMAssay Description:Inhibition of human cytochrome P450 2C9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Mus musculus (mouse))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50148708(CHEMBL120067 | [4-(2,4-Difluoro-phenylamino)-pheny...)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of murine His-Mitogen-activated protein kinase p38 alpha phosphorylation.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 9(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50148708(CHEMBL120067 | [4-(2,4-Difluoro-phenylamino)-pheny...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibit of human c-Jun N-terminal kinase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50148708(CHEMBL120067 | [4-(2,4-Difluoro-phenylamino)-pheny...)
Affinity DataIC50: >8.00E+4nMAssay Description:Inhibition of human prostaglandin G/H synthase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed