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Compile Data Set for Download or QSAR
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
19
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Target
N-lysine methyltransferase KMT5A
(Homo sapiens (Human))
University Of North Carolina At Chapel Hill
Curated by
ChEMBL
Ligand
BDBM50051117
(CHEMBL3318285)
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Affinity Data
IC50: 7.30E+3nM
Assay Description:
Inhibition of SETD8 (unknown origin) catalytic domain expressed in Escherichia coli using biotinylated H4 (1-24) peptide substrate after 1 hr by scin...
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Target
N-lysine methyltransferase KMT5A
(Homo sapiens (Human))
University Of North Carolina At Chapel Hill
Curated by
ChEMBL
Ligand
BDBM50051117
(CHEMBL3318285)
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Affinity Data
IC50: 9.00E+3nM
Assay Description:
Inhibition of methyltransferase activity of SETD8 (unknown origin) catalytic domain expressed in Escherichia coli assessed as decrease in methylation...
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Target
N-lysine methyltransferase KMT5A
(Homo sapiens (Human))
University Of North Carolina At Chapel Hill
Curated by
ChEMBL
Ligand
BDBM50051117
(CHEMBL3318285)
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Affinity Data
IC50: 3.77E+4nM
Assay Description:
Displacement of FITC-labeled H4K20me (1-24) from SETD8 (unknown origin) catalytic domain expressed in Escherichia coli by fluorescence polarization a...
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Target
Histone-lysine N-methyltransferase SETD7
(Homo sapiens (Human))
University Of North Carolina At Chapel Hill
Curated by
ChEMBL
Ligand
BDBM50051117
(CHEMBL3318285)
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Affinity Data
IC50: >1.00E+5nM
Assay Description:
Inhibition of SETD7 (unknown origin) assessed as incorporation of tritium-labeled methyl group to lysine or arginine residues of peptide substrate by...
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Target
Histone-lysine N-methyltransferase 2A
(Homo sapiens (Human))
University Of North Carolina At Chapel Hill
Curated by
ChEMBL
Ligand
BDBM50051117
(CHEMBL3318285)
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Affinity Data
IC50: >1.00E+5nM
Assay Description:
Inhibition of MLL1 (unknown origin) assessed as incorporation of tritium-labeled methyl group to lysine or arginine residues of peptide substrate by ...
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Target
Histone-lysine N-methyltransferase EHMT2
(Homo sapiens (Human))
University Of North Carolina At Chapel Hill
Curated by
ChEMBL
Ligand
BDBM50051117
(CHEMBL3318285)
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Affinity Data
IC50: >1.00E+5nM
Assay Description:
Inhibition of G9a (unknown origin) assessed as incorporation of tritium-labeled methyl group to lysine or arginine residues of peptide substrate by r...
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Target
Histone-lysine N-methyltransferase SETDB1
(Homo sapiens (Human))
University Of North Carolina At Chapel Hill
Curated by
ChEMBL
Ligand
BDBM50051117
(CHEMBL3318285)
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Affinity Data
IC50: >1.00E+5nM
Assay Description:
Inhibition of SETDB1 (unknown origin) assessed as incorporation of tritium-labeled methyl group to lysine or arginine residues of peptide substrate b...
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Target
Histone-lysine N-methyltransferase EHMT1
(Homo sapiens (Human))
University Of North Carolina At Chapel Hill
Curated by
ChEMBL
Ligand
BDBM50051117
(CHEMBL3318285)
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Affinity Data
IC50: >1.00E+5nM
Assay Description:
Inhibition of GLP (unknown origin) assessed as incorporation of tritium-labeled methyl group to lysine or arginine residues of peptide substrate by r...
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Target
Histone-lysine N-methyltransferase SUV39H2
(Homo sapiens (Human))
University Of North Carolina At Chapel Hill
Curated by
ChEMBL
Ligand
BDBM50051117
(CHEMBL3318285)
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Affinity Data
IC50: >1.00E+5nM
Assay Description:
Inhibition of SUV39H2 (unknown origin) assessed as incorporation of tritium-labeled methyl group to lysine or arginine residues of peptide substrate ...
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Target
Histone-lysine N-methyltransferase, H3 lysine-79 specific
(Homo sapiens (Human))
University Of North Carolina At Chapel Hill
Curated by
ChEMBL
Ligand
BDBM50051117
(CHEMBL3318285)
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Affinity Data
IC50: >1.00E+5nM
Assay Description:
Inhibition of DOT1L (unknown origin) by filter-based assay
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Target
Protein arginine N-methyltransferase 3 [N508S]
(Homo sapiens (Human))
University Of North Carolina At Chapel Hill
Curated by
ChEMBL
Ligand
BDBM50051117
(CHEMBL3318285)
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Affinity Data
IC50: >1.00E+5nM
Assay Description:
Inhibition of PRMT3 (unknown origin) assessed as incorporation of tritium-labeled methyl group to lysine or arginine residues of peptide substrate by...
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Target
Protein arginine N-methyltransferase 5
(Homo sapiens (Human))
University Of North Carolina At Chapel Hill
Curated by
ChEMBL
Ligand
BDBM50051117
(CHEMBL3318285)
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IC50: >1.00E+5nM
Assay Description:
Inhibition of PRMT5 (unknown origin) assessed as incorporation of tritium-labeled methyl group to lysine or arginine residues of peptide substrate by...
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Target
Protein arginine N-methyltransferase 1 [11-371]
(Homo sapiens (Human))
University Of North Carolina At Chapel Hill
Curated by
ChEMBL
Ligand
BDBM50051117
(CHEMBL3318285)
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Affinity Data
IC50: >1.00E+5nM
Assay Description:
Inhibition of PRMT1 (unknown origin) assessed as incorporation of tritium-labeled methyl group to lysine or arginine residues of peptide substrate by...
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Target
Histone-lysine N-methyltransferase KMT5B
(Homo sapiens (Human))
University Of North Carolina At Chapel Hill
Curated by
ChEMBL
Ligand
BDBM50051117
(CHEMBL3318285)
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Affinity Data
IC50: >1.00E+5nM
Assay Description:
Inhibition of SUV420H1 (unknown origin) assessed as incorporation of tritium-labeled methyl group to lysine or arginine residues of peptide substrate...
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Target
Histone-lysine N-methyltransferase KMT5C
(Homo sapiens (Human))
University Of North Carolina At Chapel Hill
Curated by
ChEMBL
Ligand
BDBM50051117
(CHEMBL3318285)
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Affinity Data
IC50: >1.00E+5nM
Assay Description:
Inhibition of SUV420H2 (unknown origin) assessed as incorporation of tritium-labeled methyl group to lysine or arginine residues of peptide substrate...
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Target
N-lysine methyltransferase SMYD2
(Homo sapiens (Human))
University Of North Carolina At Chapel Hill
Curated by
ChEMBL
Ligand
BDBM50051117
(CHEMBL3318285)
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IC50: >1.00E+5nM
Assay Description:
Inhibition of SMYD2 (unknown origin) assessed as incorporation of tritium-labeled methyl group to lysine or arginine residues of peptide substrate by...
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Target
DNA (cytosine-5)-methyltransferase 1
(Homo sapiens (Human))
University Of North Carolina At Chapel Hill
Curated by
ChEMBL
Ligand
BDBM50051117
(CHEMBL3318285)
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IC50: >1.00E+5nM
Assay Description:
Inhibition of DNMT1 (unknown origin) assessed as using dsDNA substrate by radioactive assay
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Target
N-lysine methyltransferase KMT5A
(Homo sapiens (Human))
University Of North Carolina At Chapel Hill
Curated by
ChEMBL
Ligand
BDBM50051117
(CHEMBL3318285)
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Affinity Data
Kd: 1.83E+4nM
Assay Description:
Inhibition of SETD8 (unknown origin) catalytic domain expressed in Escherichia coli by ITC assay
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Target
N-lysine methyltransferase KMT5A
(Homo sapiens (Human))
University Of North Carolina At Chapel Hill
Curated by
ChEMBL
Ligand
BDBM50051117
(CHEMBL3318285)
Copy SMILES
Copy InChI
Affinity Data
Kd: 3.60E+4nM
Assay Description:
Inhibition of SETD8 (unknown origin) catalytic domain expressed in Escherichia coli by SPR assay
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