Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 4 hits in this display   

TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL

LigandBDBM50381951(CHEMBL2023490)Copy SMILESCopy InChI

Affinity DataIC50:  10nMAssay Description:Inhibition of PDGFRbetaMore data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL

LigandBDBM50381951(CHEMBL2023490)Copy SMILESCopy InChI

Affinity DataIC50:  30nMAssay Description:Inhibition of Flt3More data for this Ligand-Target Pair

Target InfoPDBNCI pathwayReactome pathway
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL

LigandBDBM50381951(CHEMBL2023490)Copy SMILESCopy InChI

Affinity DataIC50:  183nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL

LigandBDBM50381951(CHEMBL2023490)Copy SMILESCopy InChI

Affinity DataIC50:  300nMAssay Description:Inhibition of CSF-1RMore data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI