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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
2
hits in this display
Target
Platelet-derived growth factor receptor alpha
(Homo sapiens (Human))
Kirin Brewery
Curated by
ChEMBL
Ligand
BDBM50184870
(CHEMBL205953 | N-Cyclohexyl-N'-{4-[6,7-dimethoxy-4...)
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Affinity Data
IC50: 12nM
Assay Description:
Inhibition of PDGFR alpha phosphorylation in G292 cell
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
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Target
Mast/stem cell growth factor receptor Kit
(Homo sapiens (Human))
Kirin Brewery
Curated by
ChEMBL
Ligand
BDBM50184870
(CHEMBL205953 | N-Cyclohexyl-N'-{4-[6,7-dimethoxy-4...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 22nM
Assay Description:
Inhibition of c-kit receptor phosphorylation in M07e cell
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI