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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
8
hits in this display
Target
Platelet-derived growth factor receptor beta
(Homo sapiens (Human))
Pharmaceutical Research Institute
Curated by
ChEMBL
Ligand
BDBM50115302
(4-(6,7-Dimethoxy-quinazolin-4-yl)-piperazine-1-car...)
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Affinity Data
IC50: 20nM
Assay Description:
Inhibition of Platelet-derived growth factor receptor beta
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
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Target
Receptor-type tyrosine-protein kinase FLT3
(Homo sapiens (Human))
Pharmaceutical Research Institute
Curated by
ChEMBL
Ligand
BDBM50115302
(4-(6,7-Dimethoxy-quinazolin-4-yl)-piperazine-1-car...)
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Affinity Data
IC50: 50nM
Assay Description:
Inhibition of Flt3 kinase
More data for this Ligand-Target Pair
Target Info
PDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Mast/stem cell growth factor receptor Kit
(Homo sapiens (Human))
Pharmaceutical Research Institute
Curated by
ChEMBL
Ligand
BDBM50115302
(4-(6,7-Dimethoxy-quinazolin-4-yl)-piperazine-1-car...)
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Affinity Data
IC50: 50nM
Assay Description:
Inhibition of Mast/stem cell growth factor receptor (c-Kit kinase)
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Platelet-derived growth factor receptor beta
(Homo sapiens (Human))
Pharmaceutical Research Institute
Curated by
ChEMBL
Ligand
BDBM50115302
(4-(6,7-Dimethoxy-quinazolin-4-yl)-piperazine-1-car...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 80nM
Assay Description:
Inhibition of Platelet-derived growth factor receptor beta phosphorylation
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Platelet-derived growth factor receptor alpha/beta
(Homo sapiens (Human))
Kyowa Hakko Kogyo
Curated by
ChEMBL
Ligand
BDBM50115302
(4-(6,7-Dimethoxy-quinazolin-4-yl)-piperazine-1-car...)
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Copy InChI
Affinity Data
IC50: 80nM
Assay Description:
Concentration required for 50% inhibition against autophosphorylation of Platelet-derived growth factor receptor beta in intact cells using a two sit...
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Platelet-derived growth factor receptor alpha
(Homo sapiens (Human))
Pharmaceutical Research Institute
Curated by
ChEMBL
Ligand
BDBM50115302
(4-(6,7-Dimethoxy-quinazolin-4-yl)-piperazine-1-car...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 90nM
Assay Description:
Inhibition of Platelet-derived growth factor receptor alpha
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Proto-oncogene tyrosine-protein kinase Src
(Homo sapiens (Human))
Pharmaceutical Research Institute
Curated by
ChEMBL
Ligand
BDBM50115302
(4-(6,7-Dimethoxy-quinazolin-4-yl)-piperazine-1-car...)
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Affinity Data
IC50: >3.00E+4nM
Assay Description:
Inhibition of Src protein tryrosine kinase
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Epidermal growth factor receptor
(Homo sapiens (Human))
Pharmaceutical Research Institute
Curated by
ChEMBL
Ligand
BDBM50115302
(4-(6,7-Dimethoxy-quinazolin-4-yl)-piperazine-1-car...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >3.00E+4nM
Assay Description:
Inhibition of Epidermal growth factor receptor
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI