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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
13
hits in this display
Target
Epidermal growth factor receptor
(Homo sapiens (Human))
Astrazeneca
Curated by
ChEMBL
Ligand
BDBM50183832
(CHEMBL437885 | N-(3-chloro-2-fluorophenyl)-7-metho...)
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Affinity Data
IC50: 360nM
Assay Description:
Inhibition of EGFR in presence of 2 uM ATP
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Epidermal growth factor receptor
(Homo sapiens (Human))
Astrazeneca
Curated by
ChEMBL
Ligand
BDBM50183832
(CHEMBL437885 | N-(3-chloro-2-fluorophenyl)-7-metho...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 360nM
Assay Description:
Inhibition of EGFR in presence of 2 uM ATP
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
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Target
Serine/threonine-protein kinase Chk1
(Homo sapiens (Human))
Astrazeneca
Curated by
ChEMBL
Ligand
BDBM50183832
(CHEMBL437885 | N-(3-chloro-2-fluorophenyl)-7-metho...)
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Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of CHK1
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Rho-associated protein kinase 2
(Homo sapiens (Human))
Astrazeneca
Curated by
ChEMBL
Ligand
BDBM50183832
(CHEMBL437885 | N-(3-chloro-2-fluorophenyl)-7-metho...)
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Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of ROCK2
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Mitogen-activated protein kinase 11/12/13/14
(Homo sapiens (Human))
Astrazeneca
Curated by
ChEMBL
Ligand
BDBM50183832
(CHEMBL437885 | N-(3-chloro-2-fluorophenyl)-7-metho...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of SAP kinase
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
antibodypedia
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Proto-oncogene tyrosine-protein kinase Src
(Homo sapiens (Human))
Astrazeneca
Curated by
ChEMBL
Ligand
BDBM50183832
(CHEMBL437885 | N-(3-chloro-2-fluorophenyl)-7-metho...)
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Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of Src
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human))
Astrazeneca
Curated by
ChEMBL
Ligand
BDBM50183832
(CHEMBL437885 | N-(3-chloro-2-fluorophenyl)-7-metho...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of KDR
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Mitogen-activated protein kinase 1
(Homo sapiens (Human))
Astrazeneca
Curated by
ChEMBL
Ligand
BDBM50183832
(CHEMBL437885 | N-(3-chloro-2-fluorophenyl)-7-metho...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of MAPK
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Glycogen synthase kinase-3 beta
(Homo sapiens (Human))
Astrazeneca
Curated by
ChEMBL
Ligand
BDBM50183832
(CHEMBL437885 | N-(3-chloro-2-fluorophenyl)-7-metho...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of GSK3-beta
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Tyrosine-protein kinase Lck
(Homo sapiens (Human))
Astrazeneca
Curated by
ChEMBL
Ligand
BDBM50183832
(CHEMBL437885 | N-(3-chloro-2-fluorophenyl)-7-metho...)
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Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of LCK
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Mitogen-activated protein kinase 10/8/9
(Homo sapiens (Human))
Astrazeneca
Curated by
ChEMBL
Ligand
BDBM50183832
(CHEMBL437885 | N-(3-chloro-2-fluorophenyl)-7-metho...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of JNK
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
cAMP-dependent protein kinase catalytic subunit alpha/beta/gamma
(Homo sapiens (Human))
Astrazeneca
Curated by
ChEMBL
Ligand
BDBM50183832
(CHEMBL437885 | N-(3-chloro-2-fluorophenyl)-7-metho...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of PKA
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Serine/threonine-protein kinase Sgk1
(Homo sapiens (Human))
Astrazeneca
Curated by
ChEMBL
Ligand
BDBM50183832
(CHEMBL437885 | N-(3-chloro-2-fluorophenyl)-7-metho...)
Copy SMILES
Copy InChI
Affinity Data
IC50: >1.00E+4nM
Assay Description:
Inhibition of SGK
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI