Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 2 hits in this display   

TargetTubulin beta-1 chain(Homo sapiens (Human))
University Of Salford

Curated by ChEMBL

LigandBDBM50159297((E)-3-(3''-Fluoro-4''-methoxyphenyl)-1-(3',4',5'-t...)Copy SMILESCopy InChI

Affinity DataIC50:  1.20E+3nMAssay Description:Concentration required for 50% inhibition of tubulin polymerizationMore data for this Ligand-Target Pair

Target InfoReactome pathwayKEGG
UniProtKB/SwissProt
DrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidPatentsSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetAngiotensin-converting enzyme(Oryctolagus cuniculus)
University Of Calabria

Curated by ChEMBL

LigandBDBM50159297((E)-3-(3''-Fluoro-4''-methoxyphenyl)-1-(3',4',5'-t...)Copy SMILESCopy InChI

Affinity DataIC50:  5.70E+5nMAssay Description:Inhibition of ACE in rabbit lung assessed as decrease in dansylglycine concentration after 5 mins by HPLC analysisMore data for this Ligand-Target Pair

Target InfoPDBMMDBKEGG
UniProtKB/SwissProt
B.MOADDrugBankGoogleScholar

Ligand InfoCHEMBLPC cidPC sidPatentsSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI