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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
4
hits in this display
Target
Polyunsaturated fatty acid 5-lipoxygenase
(Homo sapiens (Human))
Goethe-University Frankfurt
Curated by
ChEMBL
Ligand
BDBM50341270
((Z)-5-(4-Methoxybenzylidene)-2-phenylthiazol-5H-th...)
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Affinity Data
IC50: 150nM
Assay Description:
Inhibition of 5-lipoxygenase in S100 supernatant assessed as inhibition of LTB4 production preincubated for 15 mins measured after 10 mins by HPLC me...
Checked by Author
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Polyunsaturated fatty acid 5-lipoxygenase
(Homo sapiens (Human))
Goethe-University Frankfurt
Curated by
ChEMBL
Ligand
BDBM50341270
((Z)-5-(4-Methoxybenzylidene)-2-phenylthiazol-5H-th...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 150nM
Assay Description:
Inhibition of 5-lipoxygenase in S100 supernatant assessed as inhibition of (5(S)-hydroperoxy-6-trans-8,11,14-cis-eicosatetraenoic acid production pre...
Checked by Author
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Polyunsaturated fatty acid 5-lipoxygenase
(Homo sapiens (Human))
Goethe-University Frankfurt
Curated by
ChEMBL
Ligand
BDBM50341270
((Z)-5-(4-Methoxybenzylidene)-2-phenylthiazol-5H-th...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 530nM
Assay Description:
Inhibition of 5-lipoxygenase in human polymorphonuclear leukocytes assessed as inhibition of LTB4 production preincubated for 15 mins measured after ...
Checked by Author
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Polyunsaturated fatty acid 5-lipoxygenase
(Homo sapiens (Human))
Goethe-University Frankfurt
Curated by
ChEMBL
Ligand
BDBM50341270
((Z)-5-(4-Methoxybenzylidene)-2-phenylthiazol-5H-th...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 530nM
Assay Description:
Inhibition of 5-lipoxygenase in human polymorphonuclear leukocytes assessed as inhibition of (5(S)-hydroperoxy-6-trans-8,11,14-cis-eicosatetraenoic a...
Checked by Author
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
Ligand Info
Purchase
CHEMBL
PC cid
PC sid
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI