Compile Data Set for Download or QSAR
maximum 50k data

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 9 hits in this display   

LigandPNGBDBM50016166(CHEMBL3261517)
Affinity DataIC50:  6.80nMAssay Description:Inhibition of Cdc7/Dbf4 (unknown origin)-mediated phosphorylation of MCM2 by protein-A luminescent proximity homogenous assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCasein kinase I isoform delta(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50016166(CHEMBL3261517)
Affinity DataIC50:  104nMAssay Description:Inhibition of CK1delta (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCasein kinase I isoform alpha(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50016166(CHEMBL3261517)
Affinity DataIC50:  545nMAssay Description:Inhibition of CK1alpha (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-T1/Cyclin-dependent kinase 9(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50016166(CHEMBL3261517)
Affinity DataIC50:  729nMAssay Description:Inhibition of CDK9/Cyclin-T1 (unknown origin) by homogeneous time-resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50016166(CHEMBL3261517)
Affinity DataIC50:  862nMAssay Description:Inhibition of Cdc7/Dbf4 in human HCT116 cells assessed as reduction of MCM2 phosphorylation after 14 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50016166(CHEMBL3261517)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of Pim1 (unknown origin) by homogeneous time-resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50016166(CHEMBL3261517)
Affinity DataIC50:  1.06E+4nMAssay Description:Inhibition of CDK2/Cyclin-E (unknown origin) using maltose binding protein as substrate by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50016166(CHEMBL3261517)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of CDK1/Cyclin-B (unknown origin) by homogeneous time-resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50016166(CHEMBL3261517)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of CDK4/Cyclin-D1 (unknown origin) by homogeneous time-resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed