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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 4 hits in this display   

TargetTyrosine-protein kinase CSK(Homo sapiens (Human))
University Of Delhi

LigandPNGBDBM110206(1-[2-(Dimethylamino)ethyl]-5-(2-hydroxy-4-methoxyb...)
Affinity DataIC50:  1.25E+4nMpH: 7.5 T: 2°CAssay Description:The kinase reaction was initiated with the incubation of the 2.5 µL of the reaction cocktail (0.7 nM of His6-Src kinase domain in kinase buffer)...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-phosphoinositide-dependent protein kinase 1(Homo sapiens (Human))
University Of Delhi

LigandPNGBDBM110206(1-[2-(Dimethylamino)ethyl]-5-(2-hydroxy-4-methoxyb...)
Affinity DataIC50: >3.00E+5nMpH: 7.0Assay Description:EGFR was incubated with 8 mM MOPS (pH 7.0), 0.2 mM EDTA, 10 mM MnCl2, 0.1 mg/mL poly(Glu, Tyr) 4:1. MAPK1 was incubated with 25 mM Tris (pH 7.5), 0.0...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor [1-973](Homo sapiens (Human))
University Of Delhi

LigandPNGBDBM110206(1-[2-(Dimethylamino)ethyl]-5-(2-hydroxy-4-methoxyb...)
Affinity DataIC50: >3.00E+5nMpH: 7.0Assay Description:EGFR was incubated with 8 mM MOPS (pH 7.0), 0.2 mM EDTA, 10 mM MnCl2, 0.1 mg/mL poly(Glu, Tyr) 4:1. MAPK1 was incubated with 25 mM Tris (pH 7.5), 0.0...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
University Of Delhi

LigandPNGBDBM110206(1-[2-(Dimethylamino)ethyl]-5-(2-hydroxy-4-methoxyb...)
Affinity DataIC50: >3.00E+5nMpH: 7.0Assay Description:EGFR was incubated with 8 mM MOPS (pH 7.0), 0.2 mM EDTA, 10 mM MnCl2, 0.1 mg/mL poly(Glu, Tyr) 4:1. MAPK1 was incubated with 25 mM Tris (pH 7.5), 0.0...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed