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Compile Data Set for Download or QSAR
maximum 50k data
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
(change energy unit to
kcal/mol
)
Found
8
hits in this display
Target
Beta-2 adrenergic receptor
(Homo sapiens (Human))
Glaxosmithkline
Curated by
ChEMBL
Ligand
BDBM50267987
((+/-)-2-([3-((1,1-Dimethyl-2-[4-(methyloxy)phenyl]...)
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Affinity Data
IC50: 21nM
Assay Description:
Binding affinity to beta2 adrenoceptor
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
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Target
Sodium-dependent serotonin transporter
(Homo sapiens (Human))
Glaxosmithkline
Curated by
ChEMBL
Ligand
BDBM50267987
((+/-)-2-([3-((1,1-Dimethyl-2-[4-(methyloxy)phenyl]...)
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Copy InChI
Affinity Data
IC50: 21nM
Assay Description:
Binding affinity to serotonin transporter
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Cytochrome P450 2D6
(Homo sapiens (Human))
Glaxosmithkline
Curated by
ChEMBL
Ligand
BDBM50267987
((+/-)-2-([3-((1,1-Dimethyl-2-[4-(methyloxy)phenyl]...)
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Copy InChI
Affinity Data
IC50: 36nM
Assay Description:
Binding affinity to CYP2D6
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Extracellular calcium-sensing receptor
(Homo sapiens (Human))
Glaxosmithkline
Curated by
ChEMBL
Ligand
BDBM50267987
((+/-)-2-([3-((1,1-Dimethyl-2-[4-(methyloxy)phenyl]...)
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Copy InChI
Affinity Data
IC50: 140nM
Assay Description:
Binding affinity to human parathyroid calcium receptor 1 expressed in HEK293 4.0-7 cells by radioligand binding assay
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Sodium-dependent dopamine transporter
(Homo sapiens (Human))
Glaxosmithkline
Curated by
ChEMBL
Ligand
BDBM50267987
((+/-)-2-([3-((1,1-Dimethyl-2-[4-(methyloxy)phenyl]...)
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Affinity Data
IC50: 300nM
Assay Description:
Binding affinity to dopamine transporter
More data for this Ligand-Target Pair
Target Info
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Sodium-dependent noradrenaline transporter
(Homo sapiens (Human))
Glaxosmithkline
Curated by
ChEMBL
Ligand
BDBM50267987
((+/-)-2-([3-((1,1-Dimethyl-2-[4-(methyloxy)phenyl]...)
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Affinity Data
IC50: 300nM
Assay Description:
Binding affinity to norepinephrine transporter
More data for this Ligand-Target Pair
Target Info
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Potassium voltage-gated channel subfamily H member 2
(Homo sapiens (Human))
Glaxosmithkline
Curated by
ChEMBL
Ligand
BDBM50267987
((+/-)-2-([3-((1,1-Dimethyl-2-[4-(methyloxy)phenyl]...)
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Copy InChI
Affinity Data
IC50: 3.50E+3nM
Assay Description:
Binding affinity to human ERG
More data for this Ligand-Target Pair
Target Info
PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
B.MOAD
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI
Target
Beta-3 adrenergic receptor
(Homo sapiens (Human))
Glaxosmithkline
Curated by
ChEMBL
Ligand
BDBM50267987
((+/-)-2-([3-((1,1-Dimethyl-2-[4-(methyloxy)phenyl]...)
Copy SMILES
Copy InChI
Affinity Data
EC50: 20nM
Assay Description:
Binding affinity to beta3 adrenoceptor
More data for this Ligand-Target Pair
Target Info
PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
Patents
Similars
In Depth
Details
Article
PubMed
Copy BDB DOI