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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 8 hits in this display   

TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50267987((+/-)-2-([3-((1,1-Dimethyl-2-[4-(methyloxy)phenyl]...)
Affinity DataIC50:  21nMAssay Description:Binding affinity to beta2 adrenoceptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50267987((+/-)-2-([3-((1,1-Dimethyl-2-[4-(methyloxy)phenyl]...)
Affinity DataIC50:  21nMAssay Description:Binding affinity to serotonin transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50267987((+/-)-2-([3-((1,1-Dimethyl-2-[4-(methyloxy)phenyl]...)
Affinity DataIC50:  36nMAssay Description:Binding affinity to CYP2D6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExtracellular calcium-sensing receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50267987((+/-)-2-([3-((1,1-Dimethyl-2-[4-(methyloxy)phenyl]...)
Affinity DataIC50:  140nMAssay Description:Binding affinity to human parathyroid calcium receptor 1 expressed in HEK293 4.0-7 cells by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50267987((+/-)-2-([3-((1,1-Dimethyl-2-[4-(methyloxy)phenyl]...)
Affinity DataIC50:  300nMAssay Description:Binding affinity to dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50267987((+/-)-2-([3-((1,1-Dimethyl-2-[4-(methyloxy)phenyl]...)
Affinity DataIC50:  300nMAssay Description:Binding affinity to norepinephrine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50267987((+/-)-2-([3-((1,1-Dimethyl-2-[4-(methyloxy)phenyl]...)
Affinity DataIC50:  3.50E+3nMAssay Description:Binding affinity to human ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-3 adrenergic receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50267987((+/-)-2-([3-((1,1-Dimethyl-2-[4-(methyloxy)phenyl]...)
Affinity DataEC50:  20nMAssay Description:Binding affinity to beta3 adrenoceptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed