Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB (change energy unit to kcal/mol)

Found 3 hits in this display   

TargetAlpha-synuclein(Homo sapiens (Human))
Washington University

Curated by ChEMBL

LigandBDBM50103961(CHEMBL3593930)Copy SMILESCopy InChI

Affinity DataKi:  3.5nMAssay Description:Displacement of Thio-T from recombinant alpha-synuclein (unknown origin) expressed in Escherichia coli after 1.5 hrs by fluorescence assayMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Washington University

Curated by ChEMBL

LigandBDBM50103961(CHEMBL3593930)Copy SMILESCopy InChI

Affinity DataKi:  74nMAssay Description:Displacement of Thio-T from amyloid beta (1 to 42) (unknown origin) expressed in Escherichia coli after 1.5 hrs by fluorescence assayMore data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetMicrotubule-associated protein tau(Homo sapiens (Human))
Washington University

Curated by ChEMBL

LigandBDBM50103961(CHEMBL3593930)Copy SMILESCopy InChI

Affinity DataKi:  152nMAssay Description:Displacement of Thio-T from human recombinant tau (243 to 375) expressed in Escherichia coli BL21(DE3)RIL after 1.5 hrs by fluorescence assayMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
DrugBankGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI